{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:11:22Z","timestamp":1758474682500},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1995,5]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            Excessive sweating from cerebral infarction has been reported rarely in the available stroke literature, and its pathophysiological mechanisms and clinical significance have remained obscure. In addition, there have been no reports that medullary infarction results in only contralateral hemihyperhidrosis without ipsilateral Horner\u2019s syndrome. In the hope of increasing recognition of this phenomenon, we describe five patients with hyperhidrosis, including two patients with medullary infarction, and discuss the clinicoanatomic correlations.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Case Descriptions<\/jats:italic>\n            Contralateral hyperhidrosis occurred in two patients with large strokes involving both superficial cortical and deep subcortical structures of the middle cerebral artery territory and in two patients with medullary infarctions. Bilateral hyperhidrosis of the face was noted in one patient with basilar artery thrombosis and bilateral cerebellar and pontine infarctions. The hyperhidrosis typically involved the face and arm and was transient, lasting from 2 days to 2 months. No associated Horner\u2019s syndrome, hypothalamic dysfunction, or other autonomic dysfunction was observed.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            The phenomenon of hyperhidrosis might be attributed to a lesion of a putative sympathoinhibitory pathway that controls sweating. This pathway might originate in the cortex, possibly in the operculum, and make terminal connections with the contralateral thoracic spinal cord. Our observations suggest that the fibers of this putative pathway may be very close to the corticospinal tract.\n          <\/jats:p>","DOI":"10.1161\/01.str.26.5.896","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"896-899","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Contralateral Hyperhidrosis After Cerebral Infarction"],"prefix":"10.1161","volume":"26","author":[{"given":"Beum-Saeng","family":"Kim","sequence":"first","affiliation":[{"name":"From the Department of Neurology, Catholic University Medical College, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeong-In","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Catholic University Medical College, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwang-Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Catholic University Medical College, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.23.9.1519281"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.6.1211"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.11.1679"},{"key":"e_1_3_1_4_2","unstructured":"Appenzeller O. Sweat gland activity and disturbances of sweating. In: Appenzeller O ed. The Autonomic Nervous System. 4th ed. New York NY: Elsevier Science Publishing Co Inc; 1990:117-140."},{"key":"e_1_3_1_5_2","first-page":"454","volume":"32","year":"1992","unstructured":"Sakashita Y, Kakuta K, Kakuma K, Matsuda H. Unilateral persistent hyperhidrosis after ischemic stroke [in Japanese]. Rinsho Shinkeigaku. 1992;32:454-456.","journal-title":"Rinsho Shinkeigaku"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.12.1182"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.3.277"},{"key":"e_1_3_1_8_2","first-page":"718","volume":"32","year":"1992","unstructured":"Mon Y, Mizotani M. A case of hemi-hyperhidrosis and non-paralytic pontine exotropia due to brainstem infarction [in Japanese]. Rinsho Shinkeigaku. 1992;32:718-721.","journal-title":"Rinsho Shinkeigaku"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500210038005"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1979.00500370043006"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.1.8418531"},{"key":"e_1_3_1_12_2","first-page":"778","volume":"11","year":"1960","unstructured":"Peterman AF, Siekert RG. The lateral medullary (Wallenberg) syndrome: clinical features and prognosis. Med Clin North Am. 1960;11:778-790.","journal-title":"Med Clin North Am"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.11.9.778"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540060049016"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.25.7.8023356"},{"key":"e_1_3_1_16_2","unstructured":"Adams RD Victor M. Cerebrovascular diseases. In: Adams RD Victor M eds. Principles of Neurology. 5th ed. New York NY: McGraw-Hill Publishing Co; 1993:669-748."}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.26.5.896","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:18:06Z","timestamp":1715552286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.26.5.896"}},"subtitle":["Clinicoanatomic Correlations in Five Cases"],"short-title":[],"issued":{"date-parts":[[1995,5]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1995,5]]}},"alternative-id":["10.1161\/01.STR.26.5.896"],"URL":"https:\/\/doi.org\/10.1161\/01.str.26.5.896","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,5]]},"assertion":[{"value":"1994-11-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-02-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}