{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:30:21Z","timestamp":1768570221580,"version":"3.49.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Symptoms interpreted as unilateral disturbances of autonomic function, such as coldness, dryness, sweating, and trophic changes, are well known but incompletely understood clinical problems after stroke. The present study provides data related to the incidence and mechanisms behind such symptoms.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            Temperature perception thresholds, skin temperatures, evaporation rates, and skin blood flow responses were measured bilaterally in 37 stroke patients aged 58\u00b113 years (mean\u00b1SD) and in a control group of 15 patients aged 64\u00b115 years with a single transient ischemic attack.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Of the 37 stroke patients, 43% reported a sensation of coldness in the contralesional side of the body. Basal skin blood flow and temperature were relatively lower in the contralesional side. There was an excess of evaporation in the contralesional side after brain stem lesions and in the ipsilesional side after hemispheric lesions. Vasomotor reflex asymmetries occurred in 34% of the patients and were due to weak vasodilator or vasoconstrictor reflexes in the ipsilesional side. These abnormalities correlated significantly to sensations of unilateral coldness, hypalgesia, and thermohypesthesia in the contralesional side and anatomically to lesions in spino-thalamo-cortical pathways.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            Focal central nervous system lesions due to stroke may result in symptoms and measurable evidence of unilateral disturbance of skin sympathetic function. Vasomotor asymmetries are probably due to lesions of vasomotor pathways descending uncrossed. Subjective coldness may be due to disturbed central processing.\n          <\/jats:p>","DOI":"10.1161\/01.str.26.8.1379","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1379-1385","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":37,"title":["Autonomic and Thermal Sensory Symptoms and Dysfunction After Stroke"],"prefix":"10.1161","volume":"26","author":[{"given":"Hans","family":"Naver","sequence":"first","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Blomstrand","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Ekholm","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christer","family":"Jensen","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Karlsson","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Gunnar","family":"Wallin","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (H.N., C.B.) and Clinical Neurophysiology (H.N., T.K., G.W.), Institute of Clinical Neuroscience, and the Division of Neuroradiology (S.E., C.J.), Department of Radiology, Sahlgren Hospital, University of Go\u0308teborg, Sweden."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.11.1679"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.23.9.1519281"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.6.1211"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.9.8362436"},{"key":"e_1_3_2_5_2","first-page":"1097","volume":"76","year":"1933","unstructured":"Olsen A. Hemiplegi og hudtemperatur. 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