{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:59:24Z","timestamp":1791896364078,"version":"4.3.4"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Vascular dementia (VD) has been an ill-defined term thus far. Recently detailed criteria for the diagnosis of VD have been proposed (Alzheimer\u2019s Disease Diagnostic and Treatment Centers [ADDTC], 1992;\n            <jats:italic>Diagnostic and Statistical Manual of Mental Disorders,<\/jats:italic>\n            4th edition [DSM-IV], 1994;\n            <jats:italic>International Classification of Diseases,<\/jats:italic>\n            10th revision [ICD-10], 1992, 1993; and National Institute of Neurological Disorders and Stroke\u2013Association Internationale pour la Recherche et l\u2019Enseignement en Neurosciences [NINDS-AIREN], 1993). Until now the clinical feasibility of these diagnostic guidelines has not been evaluated.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            This study aimed to compare these criteria in an unselected sample of 167 elderly patients (mean age, 72.0\u00b19.9 years) admitted with probable dementia.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            The number of cases that could be classified as VD differed widely between the various diagnostic guidelines. According to DSM-IV criteria, 45 cases were diagnosed as VD. Twenty-one cases fulfilled the ICD-10 research criteria, but only 12 met the NINDS-AIREN criteria for VD. Twenty-three cases were classified as ischemic VD as defined by the ADDTC criteria. The concordance was very poor since only 5 cases met the criteria for VD of all diagnostic guidelines.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            Our results show that the classification according to different diagnostic guidelines yields rather distinct groups of patients. The reasons responsible for these findings are as follows: (1) different criteria for dementia, (2) limitation to ischemic VD in the ADDTC criteria, (3) no further differentiation of VD into subtypes according to CT or MRI findings (DSM-IV), and (4) the multifactorial etiopathology of VD. Major diagnostic difficulties ensue from the very frequent cases with white matter lesions, since their etiology and classification remain widely unknown.\n          <\/jats:p>","DOI":"10.1161\/01.str.27.1.30","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:10:52Z","timestamp":1308341452000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":181,"title":["Comparison of Different Diagnostic Criteria for Vascular Dementia (ADDTC, DSM-IV, ICD-10, NINDS-AIREN)"],"prefix":"10.1161","volume":"27","author":[{"given":"Tilman","family":"Wetterling","sequence":"first","affiliation":[{"name":"From the Department of Psychiatry and the Institute of Radiology (K.-J.B), University School of Medicine, Lu\u0308beck, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf-Dieter","family":"Kanitz","sequence":"additional","affiliation":[{"name":"From the Department of Psychiatry and the Institute of Radiology (K.-J.B), University School of Medicine, Lu\u0308beck, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Jochen","family":"Borgis","sequence":"additional","affiliation":[{"name":"From the Department of Psychiatry and the Institute of Radiology (K.-J.B), University School of Medicine, Lu\u0308beck, FRG."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02189530"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000116237"},{"key":"e_1_3_1_3_2","first-page":"181","volume":"5","year":"1994","unstructured":"Wallin A, Blennow K. 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