{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:57:25Z","timestamp":1761541045875},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1996,12]]},"abstract":"<jats:p>\n            <jats:italic>Background<\/jats:italic>\n            Afibrinogenemia, a rare coagulation disorder, has not been associated with vertebral artery dissections.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Case Description<\/jats:italic>\n            A 28-year-old woman with afibrinogenemia developed spontaneous neck pain followed by a right medullary infarction, and MR angiography showed extensive bilateral vertebral artery dissection. She was treated with fibrinogen replacement and anticoagulants and showed a favorable evolution, with only mild residual right upper arm incoordination.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            In this patient spontaneous bilateral vertebral artery dissection complicated afibrinogenemia. Since anticoagulant therapy is usually indicated for arterial dissection, this association created a therapeutic problem. This patient received anticoagulants with fibrinogen replacement, which resulted in a favorable evolution.\n          <\/jats:p>","DOI":"10.1161\/01.str.27.12.2325","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:10:52Z","timestamp":1308341452000},"page":"2325-2327","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":28,"title":["Bilateral Vertebral Artery Dissection in a Patient With Afibrinogenemia"],"prefix":"10.1161","volume":"27","author":[{"given":"Juan C.","family":"Garci\u0301a-Monco\u0301","sequence":"first","affiliation":[{"name":"the Neurology Department and Magnetic Resonance Unit \u201cOsatek\u201d (G.F.C.), Hospital de Galdacano, Vizcaya, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo Ferna\u0301ndez","family":"Canto\u0301n","sequence":"additional","affiliation":[{"name":"the Neurology Department and Magnetic Resonance Unit \u201cOsatek\u201d (G.F.C.), Hospital de Galdacano, Vizcaya, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian Go\u0301mez","family":"Beldarrain","sequence":"additional","affiliation":[{"name":"the Neurology Department and Magnetic Resonance Unit \u201cOsatek\u201d (G.F.C.), Hospital de Galdacano, Vizcaya, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","unstructured":"Gralnick HR. Congenital abnormalities of fibrinogen. In: Williams WJ Beutler E Ersley AJ Lichtman MA eds. Hematology. New York NY: McGraw-Hill Publishing Co; 1990:1473-1490."},{"key":"e_1_3_1_2_2","unstructured":"Mokri B. Dissections of cervicocephalic arteries. In: Meyer FB ed. Sundt's Occlusive Cerebrovascular Disease. 2nd ed. Philadelphia Pa: WB Saunders; 1994:45-70."},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.11.8236342"},{"key":"e_1_3_1_4_2","unstructured":"Saver JL Easton JD Hart RG. Dissections and trauma of cervicocerebral arteries. In: Barnett HJM Mohr JP Stein BM Yatsu FM eds. Stroke: Pathophysiology Diagnosis and Treatment. New York NY: Churchill Livingstone Inc; 1992:671-688."},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.7.993"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1989.hed2909560.x"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.6.8506553"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.1.8418536"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.158.1.3940374"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.27.12.2325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:10:12Z","timestamp":1715551812000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.27.12.2325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,12]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1996,12]]}},"alternative-id":["10.1161\/01.STR.27.12.2325"],"URL":"https:\/\/doi.org\/10.1161\/01.str.27.12.2325","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,12]]},"assertion":[{"value":"1996-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-08-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}