{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:26:12Z","timestamp":1780050372670,"version":"3.53.1"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1996,3]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            The purpose of this study was to elucidate the prevalence and degree of asymptomatic occlusive lesions in the carotid and intracranial arteries in Japanese patients with ischemic heart disease (IHD).\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            We performed carotid and intracranial MR angiography (MRA) on 67 patients (49 men, 18 women; age range, 40 to 78 years; mean age, 60.1 years) who had received selective coronary angiography for the clinical diagnosis of IHD. On the basis of these images, degree of stenosis in the regions of the bilateral carotid artery bifurcation and five regions of the intracranial arteries, ie, bilateral intracranial portions of the internal carotid arteries and the middle cerebral arteries and the basilar artery were estimated.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Stenosis of more than 25% narrowing of the diameter of the target arteries was found in 15 patients (22.4%) in the extracranial carotid arteries and in 11 patients (16.4%) in the intracranial arteries. Most of the stenotic lesions were mild. The incidence of extracranial carotid stenosis and the severity of coronary atherosclerosis showed a significant correlation. The mean age of the patients with intracranial arterial lesions was statistically higher than those without intracranial lesions.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            Our data suggest that asymptomatic occlusive lesions in the carotid and intracranial arteries are fairly common in Japanese patients with IHD, although the degree of stenosis is relatively mild. Coexistence of carotid atherosclerosis should be suspected in IHD patients with severe coronary atherosclerosis, and the possibility of atherosclerosis in the intracranial arteries should be considered in aged IHD patients.\n          <\/jats:p>","DOI":"10.1161\/01.str.27.3.393","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"393-397","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":35,"title":["Asymptomatic Occlusive Lesions of Carotid and Intracranial Arteries in Japanese Patients With Ischemic Heart Disease"],"prefix":"10.1161","volume":"27","author":[{"given":"Toshiyuki","family":"Uehara","sequence":"first","affiliation":[{"name":"From the Neurology Service (T.U., M.T.) and Division of Cardiology (T.H., H.K.), Hyogo Brain and Heart Center at Himeji, and Division of Disability Science, Tohoku University Graduate School of Medicine, Sendai (A.Y.), Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayasu","family":"Tabuchi","sequence":"additional","affiliation":[{"name":"From the Neurology Service (T.U., M.T.) and Division of Cardiology (T.H., H.K.), Hyogo Brain and Heart Center at Himeji, and Division of Disability Science, Tohoku University Graduate School of Medicine, Sendai (A.Y.), Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takatoshi","family":"Hayashi","sequence":"additional","affiliation":[{"name":"From the Neurology Service (T.U., M.T.) and Division of Cardiology (T.H., H.K.), Hyogo Brain and Heart Center at Himeji, and Division of Disability Science, Tohoku University Graduate School of Medicine, Sendai (A.Y.), Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Kurogane","sequence":"additional","affiliation":[{"name":"From the Neurology Service (T.U., M.T.) and Division of Cardiology (T.H., H.K.), Hyogo Brain and Heart Center at Himeji, and Division of Disability Science, Tohoku University Graduate School of Medicine, Sendai (A.Y.), Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Yamadori","sequence":"additional","affiliation":[{"name":"From the Neurology Service (T.U., M.T.) and Division of Cardiology (T.H., H.K.), Hyogo Brain and Heart Center at Himeji, and Division of Disability Science, Tohoku University Graduate School of Medicine, Sendai (A.Y.), Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03340210040022"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.28.8.746"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.19.11.3055443"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.17.4.3526645"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.15.1.6695431"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.15.1.6695428"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.79.3.2783893"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121223"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.20.9.2672424"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.18.6.3686596"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.10.5.714"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.17.2.3083535"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.82.4.2205416"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000108509"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000107852"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.22.6.2057968"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.23.7.1615542"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1993.00540070026009"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.3995\/jstroke.16.109"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.185.3.1438743"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.179.3.2027995"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331979304400106"},{"key":"e_1_3_1_23_2","first-page":"473","volume":"50","year":"1984","unstructured":"Andersen CA, Weiser HC, Greenfield NE. Asymptomatic carotid arterial disease in patients presenting with angiographically proven coronary artery disease. Am J Surg.. 1984;50:473-475.","journal-title":"Am J Surg."},{"key":"e_1_3_1_24_2","first-page":"1075","volume":"90","year":"1981","unstructured":"Barnes RW, Liebman PR, Marszalek PB, Kirk CL, Goldman MH. The natural history of asymptomatic carotid disease in patients undergoing cardiovascular surgery. Surgery. 1981;90:1075-1083.","journal-title":"Surgery"},{"key":"e_1_3_1_25_2","first-page":"819","volume":"31","year":"1991","unstructured":"Tanaka H, Ishida M, Nishino M, Fukunaga R, Yasuno M, Sueyoshi K, Yamada Y, Abe H. Carotid atherosclerosis and silent cerebral infarction in patients with coronary atherosclerosis. J Jpn Coll Angiol. 1991;31:819-824.","journal-title":"J Jpn Coll Angiol"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.27.5.929"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.1.4.250"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.6.8506547"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331979304400602"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.21.11.2237950"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.2.8421820"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.27.3.393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T08:09:11Z","timestamp":1738829351000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.27.3.393"}},"subtitle":["Evaluation by Brain Magnetic Resonance Angiography"],"short-title":[],"issued":{"date-parts":[[1996,3]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,3]]}},"alternative-id":["10.1161\/01.STR.27.3.393"],"URL":"https:\/\/doi.org\/10.1161\/01.str.27.3.393","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,3]]},"assertion":[{"value":"1995-07-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-11-29","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-11-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-03-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}