{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:05:48Z","timestamp":1792098348865,"version":"4.4.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1996,7]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Our aim was to evaluate fluid-attenuated inversion recovery (FLAIR) sequence in the diagnosis of cerebral infarction with MRI.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            A retrospective review was undertaken of 50 consecutive MRI studies ordered for suspected cerebrovascular accident. All studies included FLAIR and rapid acquisition with relaxation enhancement (RARE) T\n            <jats:sub>2<\/jats:sub>\n            -weighted spin-echo sequences. The two sequences were compared independently by four observers at two different institutions. Detectability of lesions and image quality were scored.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Overall, FLAIR sequences proved superior in 10 patients, detecting acute cortical infarcts missed with RARE spin-echo technique in five patients. In five additional patients, improved characterization of chronic infarction and improved detection of microangiopathic deep hemispheric changes were observed. One brain stem infarct was missed with the FLAIR sequence.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            FLAIR offers advantages in detection of acute infarcts affecting the cortical ribbon, is a useful, rapid adjunct to conventional T\n            <jats:sub>2<\/jats:sub>\n            -weighted spin-echo sequences, and has the potential to replace these in the future.\n          <\/jats:p>","DOI":"10.1161\/01.str.27.7.1187","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1187-1191","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":119,"title":["Fluid-Attenuated Inversion Recovery (FLAIR) for Assessment of Cerebral Infarction"],"prefix":"10.1161","volume":"27","author":[{"given":"Michael","family":"Brant-Zawadzki","sequence":"first","affiliation":[{"name":"From the Hoag Memorial Hospital, Newport Beach (M.B.-Z., D.A., M.D., G.S.), and Long Beach Memorial Hospital (W.G.B.) (Calif)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Atkinson","sequence":"additional","affiliation":[{"name":"From the Hoag Memorial Hospital, Newport Beach (M.B.-Z., D.A., M.D., G.S.), and Long Beach Memorial Hospital (W.G.B.) (Calif)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Detrick","sequence":"additional","affiliation":[{"name":"From the Hoag Memorial Hospital, Newport Beach (M.B.-Z., D.A., M.D., G.S.), and Long Beach Memorial Hospital (W.G.B.) (Calif)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William G.","family":"Bradley","sequence":"additional","affiliation":[{"name":"From the Hoag Memorial Hospital, Newport Beach (M.B.-Z., D.A., M.D., G.S.), and Long Beach Memorial Hospital (W.G.B.) (Calif)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Scidmore","sequence":"additional","affiliation":[{"name":"From the Hoag Memorial Hospital, Newport Beach (M.B.-Z., D.A., M.D., G.S.), and Long Beach Memorial Hospital (W.G.B.) (Calif)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","first-page":"307","volume":"138","year":"1982","unstructured":"Wall SD, Brant-Zawadzki M, Jeffrey RB, Barnes B. High frequency CT findings within 24 hours after cerebral infarction. Am J Radiol. 1982;138:307-311.","journal-title":"Am J Radiol"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.176.3.2389039"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.135.3.7384452"},{"key":"e_1_3_1_4_2","first-page":"7","volume":"7","year":"1986","unstructured":"Brant-Zawadzki M, Pereira B, Weinstein P, Moore S, Kucharczyk W, Berry I, McNamara M, Derugin N. MR imaging of acute experimental ischemia in cats. AJNR Am J Neuroradiol. 1986;7:7-11.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910190220"},{"key":"e_1_3_1_6_2","first-page":"621","volume":"12","year":"1991","unstructured":"Yuh WT, Crain MR, Loes DJ, Greene GM, Ryals TJ, Sato Y. MR imaging of cerebral ischemia: findings in the first 24 hours. AJNR Am J Neuroradiol. 1991;12:621-629.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_1_7_2","first-page":"611","volume":"12","year":"1991","unstructured":"Bryan RN, Levy LM, Whitlow WD, Killian JM, Preziosi TJ, Rosario JA. Diagnosis of acute cerebral infarction: comparison of CT and MRI imaging. AJNR Am J Neuroradiol. 1991;12:611-620.","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.26.5.807"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.23.5.1579963"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199207000-00002"},{"key":"e_1_3_1_11_2","first-page":"1555","volume":"13","year":"1992","unstructured":"De Coene B, Hajnal JV, Gatehouse P, Longmore DB, White SJ, Oatridge A, Pennock JM, Young IR, Bydder GM. MR of the brain using fluid-attenuated inversion recovery (FLAIR) pulse sequences. AJNR Am J Neuroradiol. 1992;13:1555-1564.","journal-title":"Am J Neuroradiol"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910280116"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.193.1.8090888"},{"key":"e_1_3_1_14_2","unstructured":"Hajnal JV De Coene B Cowan FM. Application of prolonged inversion and echo time inversion recovery (PIETIR) pulse sequences to diagnosis of disease of the brain. In: Book of Abstracts: Society of Magnetic Resonance in Medicine. Berkeley Calif: Society of Magnetic Resonance in Medicine; 1992:1007. Abstract."},{"key":"e_1_3_1_15_2","unstructured":"den Boer JA. Salverda P Peters TR Prevo RL. Multislice turbo-FLAIR in brain studies of multiple sclerosis. In: Book of Abstracts: Society of Magnetic Resonance in Medicine. Berkeley Calif: Society of Magnetic Resonance in Medicine; 1993:328. Abstract."}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.27.7.1187","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:26:56Z","timestamp":1715552816000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.27.7.1187"}},"subtitle":["Initial Clinical Experience in 50 Patients"],"short-title":[],"issued":{"date-parts":[[1996,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1996,7]]}},"alternative-id":["10.1161\/01.STR.27.7.1187"],"URL":"https:\/\/doi.org\/10.1161\/01.str.27.7.1187","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7]]},"assertion":[{"value":"1996-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}