{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:56:54Z","timestamp":1762865814846},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1996,9]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Carotid angiography is associated with a 1% risk of major stroke. Recently, transcranial Doppler ultrasonography (TCD) has shown cerebral microemboli during carotid angiography. To determine their significance, we correlated the number of microemboli during angiography with clinical characteristics, angiography findings, and preangiography and postangiography cerebral magnetic resonance imaging (MRI).\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            One middle cerebral artery was monitored with TCD in 24 patients during angiography for carotid territory ischemia. The number of microemboli was correlated with angiographic and clinical characteristics. T2-weighted cerebral MRI was performed before and \u226448 hours after angiography, and the number of new ischemic lesions was determined in a blinded review.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Microemboli were seen in all patients, with an average of 51 per procedure (range, 12 to 154). The majority of microemboli had signal characteristics typical of air. Sixteen of the 24 patients had both preangiography and postangiography MRI. One of 24 patients had an angiographic stroke, with a single new thalamic lesion on MRI. No other patient had a new lesion. The microembolus count correlated with the angiographic contrast volume (\n            <jats:italic>P<\/jats:italic>\n            &lt;.001) but not with any other radiological or clinical characteristic.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            This study confirmed the presence of numerous cerebral microemboli during carotid angiography. The microembolic signal characteristics and the correlation with contrast volume indicate that introduced air is the cause. These microemboli are usually clinically silent and do not lead to new changes on cerebral MRI.\n          <\/jats:p>","DOI":"10.1161\/01.str.27.9.1543","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1543-1547","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":45,"title":["Microemboli During Carotid Angiography"],"prefix":"10.1161","volume":"27","author":[{"given":"Richard P.","family":"Gerraty","sequence":"first","affiliation":[{"name":"the Neurosciences Department, Royal Melbourne Hospital, Parkville, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David N.","family":"Bowser","sequence":"additional","affiliation":[{"name":"the Neurosciences Department, Royal Melbourne Hospital, Parkville, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Infeld","sequence":"additional","affiliation":[{"name":"the Neurosciences Department, Royal Melbourne Hospital, Parkville, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"the Neurosciences Department, Royal Melbourne Hospital, Parkville, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Davis","sequence":"additional","affiliation":[{"name":"the Neurosciences Department, Royal Melbourne Hospital, Parkville, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.21.2.2406993"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.18.6.3686597"},{"key":"e_1_3_2_3_2","first-page":"124","volume":"30","year":"1990","unstructured":"Staudacher T, Prey N, Sonntag W, Stoeter P. Zur Grundlage der Ultraschallph\u00e4nomene w\u00e4hrend der Injektion von R\u00f6ntgenkontrastmitteln. Radiologe.. 1990;30:124-129.","journal-title":"Radiologe."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90561-T"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.161.5.7903842"},{"key":"e_1_3_2_6_2","first-page":"115","volume":"4","year":"1986","unstructured":"Pugsley W. The use of Doppler ultrasound in the assessment of microemboli during cardiac surgery. Perfusion.. 1986;4:115-122.","journal-title":"Perfusion."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)62077-2"},{"key":"e_1_3_2_8_2","first-page":"283","volume":"9","year":"1990","unstructured":"Tegeler CH, Hitchings LP, Eicke M, Leighton J, Fredericks RK, Downes TR, Stump DA, Burke GL. Microemboli detection in stroke associated with atrial fibrillation. J Cardiovasc Tech.. 1990;9:283-284. Abstract.","journal-title":"J Cardiovasc Tech."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.25.11.7974534"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.26.11.2067"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.4.615"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.26.2.210"},{"key":"e_1_3_2_13_2","first-page":"128","volume":"3","year":"1994","unstructured":"Grosset DG, Cowburn P, Georgiadis D, Dargie HJ, Faichney A, Lee KR. Ultrasound detection of cerebral emboli in patients with prosthetic heart valves. J Heart Valve Dis.. 1994;3:128-132.","journal-title":"J Heart Valve Dis."},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.25.8.7913774"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.22.2.2003290"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.1.8418529"},{"key":"e_1_3_2_17_2","first-page":"447","volume":"28","year":"1990","unstructured":"Moody DM, Bell MA, Challa VR, Johnston WE, Prough DS. Brain microemboli during cardiac surgery or aortography. Ann Neurol.. 1990;28:447-486.","journal-title":"Ann Neurol."},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.4.662"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.22.6.2057968"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.26.6.1123"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0301-5629(94)90100-7"},{"key":"e_1_3_2_22_2","unstructured":"Walsh K Drury J Worcester M. Cognitive function following coronary artery bypass surgery. In: Donnan GA Berkovic SF Vajda FJE eds. Stroke. Proceedings of workshop held at the Austin Hospital John Lindell Lecture Theatre Melbourne Australia. 1988:133-138."},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91412-F"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.25.5.7909393"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.27.9.1543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:39:01Z","timestamp":1715553541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.27.9.1543"}},"subtitle":["Association With Stroke Risk Factors or Subsequent Magnetic Resonance Imaging Changes?"],"short-title":[],"issued":{"date-parts":[[1996,9]]},"references-count":24,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1996,9]]}},"alternative-id":["10.1161\/01.STR.27.9.1543"],"URL":"https:\/\/doi.org\/10.1161\/01.str.27.9.1543","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,9]]},"assertion":[{"value":"1995-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-06-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}