{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:14:47Z","timestamp":1760955287113},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1997,5]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            The clinical presentation of middle cerebral artery (MCA) stenosis, a rarely diagnosed condition, is not well known. The aim of this study was to analyze the stroke patterns of patients with isolated MCA stenosis.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            Twenty-two patients with cerebral infarcts due to isolated MCA stenosis were analyzed with respect to their clinical syndrome, and cerebral lesions were assessed by neuroimaging. MCA stenosis was diagnosed by transcranial Doppler sonography (TCD) in 16, by TCD and digital subtraction angiography (DSA) in 4, and by DSA alone in 2 patients.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Ten patients (45.5%) had lacunar syndromes, suggesting small-vessel disease, and 12 patients (55.5%) showed signs and symptoms of cortical dysfunction. Cerebral CT or MRI showed no lesion in 2 patients, small deep infarcts in 10, large striatocapsular infarcts in 2, combined piomedullary and striatocapsular infarcts in 4, piomedullary branch infarcts in 3, and MCA trunk infarct in 1.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            The results suggest an association between MCA stenosis and (1) lacunar infarcts and (2) the occurrence of piomedullary MCA branch infarcts alone or in combination with subcortical infarcts. The clinical syndromes and the radiological findings correspond in most cases.\n          <\/jats:p>","DOI":"10.1161\/01.str.28.5.1022","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1022-1027","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Cerebral Infarcts Related to Isolated Middle Cerebral Artery Stenosis"],"prefix":"10.1161","volume":"28","author":[{"given":"P. A.","family":"Lyrer","sequence":"first","affiliation":[{"name":"From the Department of Neurology and Division of Neuroradiology (E.W.R.), University Hospital Basel (Switzerland)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Engelter","sequence":"additional","affiliation":[{"name":"From the Department of Neurology and Division of Neuroradiology (E.W.R.), University Hospital Basel (Switzerland)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. W.","family":"Radu\u0308","sequence":"additional","affiliation":[{"name":"From the Department of Neurology and Division of Neuroradiology (E.W.R.), University Hospital Basel (Switzerland)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. J.","family":"Steck","sequence":"additional","affiliation":[{"name":"From the Department of Neurology and Division of Neuroradiology (E.W.R.), University Hospital Basel (Switzerland)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"unstructured":"Mohr JP Gautier JC Hier DB. Middle cerebral artery disease. In: Barnett HRM Mohr JP Stein BM Yatsu FM eds. Stroke: Pathophysiology Diagnosis and Management. 2nd ed. New York NY: Churchill Livingstone; 1992:361-417.","key":"e_1_3_1_1_2"},{"doi-asserted-by":"publisher","key":"e_1_3_1_2_2","DOI":"10.1159\/000108494"},{"unstructured":"Saver JF Biller J. Arterial and topographic syndromes: superficial middle cerebral artery. In: Bogousslavsky J Caplan L eds. Stroke Syndromes. 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