{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:16:31Z","timestamp":1790810191270,"version":"4.1.0"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1997,5]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Coronary artery disease is prevalent in stroke patients and is an important factor affecting rehabilitation and health outcomes. However, the presence of neurological deficits in gait and balance has discouraged systematic application of exercise testing and prescription in the stroke population. We evaluated a novel graded treadmill stress test in paretic stroke patients and tested floor walking as a predictor of adequate neurological function to perform the treadmill test.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            Patients (n=31) with residual paretic gait deficits after ischemic stroke were evaluated with graded treadmill at gait velocities individualized to functional mobility observed during an initial zero-incline treadmill tolerance test.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Most patients (30\/31) tolerated testing, achieving mean heart rates of 129\u00b114 beats per minute (mean\u00b1SD), representing 84\u00b110% of maximal age-predicted heart rate. Evidence for asymptomatic myocardial ischemia was found in 29% of those without known coronary artery disease. Exercise termination was more often due to generalized fatigue than cardiopulmonary intolerance (23\/31 versus 4\/31;\n            <jats:italic>P<\/jats:italic>\n            &lt;.0001) or hemiparetic leg fatigue (1\/31;\n            <jats:italic>P<\/jats:italic>\n            &lt;.0001). Floor walking across a wide range of velocities (0.25 to 2.5 mph) demonstrated a strong linear relation with treadmill velocities (n=24;\n            <jats:italic>r<\/jats:italic>\n            =.80;\n            <jats:italic>P<\/jats:italic>\n            &lt;.0001); all patients floor walking at \u22650.5 mph had adequate neuromotor function to perform the exercise test.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            These findings suggest that graded treadmill exercise testing, with proper safety precautions, can be used to assess cardiopulmonary function in paretic stroke patients. A simple floor-walking test predicts adequate neurological function to perform the exercise test. Exercise capacity is most limited by generalized fatigue and not by the paretic limb, supporting a rationale for endurance training in this population.\n          <\/jats:p>","DOI":"10.1161\/01.str.28.5.988","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"988-992","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":116,"title":["Low-Velocity Graded Treadmill Stress Testing in Hemiparetic Stroke Patients"],"prefix":"10.1161","volume":"28","author":[{"given":"R. F.","family":"Macko","sequence":"first","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. I.","family":"Katzel","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Yataco","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. D.","family":"Tretter","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. A.","family":"DeSouza","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. R.","family":"Dengel","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. V.","family":"Smith","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. H.","family":"Silver","sequence":"additional","affiliation":[{"name":"From the Geriatrics Service and the Geriatrics Research, Education, and Clinical Center (R.F.M., L.I.K., A.Y., L.D.T., C.A.D., D.R.D., K.H.S.), Baltimore Department of Veterans Affairs Medical Center, and Departments of Neurology (R.F.M., K.H.S.) and Physical Therapy (G.V.S.), University of Maryland School of Medicine, Baltimore, Md."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","unstructured":"Fletcher GF Schlant RC. The exercise test. In: Schlant RC Alexander RW eds. The Heart: Arteries and Veins. 8th ed. New York NY: McGraw-Hill Publishing Co; 1994;423-440."},{"key":"e_1_3_2_2_2","unstructured":"Kenney WL Humphrey RH Bryant CX Mahler DA Froelicher VF Miller NH York TD. American College of Sports Medicine: Guidelines for Exercise Testing and Prescription. 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