{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:48:00Z","timestamp":1790099280533,"version":"4.0.1"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            Although recent studies suggest a high prevalence of obstructive sleep apnea (OSA) in patients with acute stroke, a systematic characterization of sleep-disordered breathing based on the severity and topography of stroke has not been performed.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            We prospectively studied 39 noncomatose adult subjects (15 women, 24 men; mean age, 57 years) with a first acute stroke. Sleep history, cardiovascular risk factors, stroke severity as estimated by the Scandinavian Stroke Scale, and extent of stroke demonstrated on a computed tomographic or magnetic resonance imaging scan of the brain were assessed. Polysomnography was performed a mean of 10 days (range, 1 to 49 days) after stroke onset. Monitoring of breathing during wakefulness, non\u2013rapid eye movement sleep, and rapid eye movement sleep included measurements of nasal\/oral airflow, respiratory effort, and oxygen saturation.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            Breathing was abnormal during wakefulness in 7 (18%) subjects and during sleep in 26 (67%). Obstructive sleep apnea (apnea-hypopnea index &gt;10) was found in 14 subjects, Cheyne-Stokes\u2013like breathing was observed in 4, and a combination of obstructive sleep apnea and Cheyne-Stokes\u2013like breathing was observed in 7. Sustained tachypnea and ataxic breathing were rare. No significant differences were found in age, body mass index, history of snoring or hypersomnia, or stroke topography or severity between subjects with and without sleep-disordered breathing. Prevalence and severity of breathing disturbances were also similar between patients with supratentorial stroke (n=28) and those with infratentorial (n=11) stroke.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            Sleep-disordered breathing is frequent in patients with acute stroke, rarely has localizing value, and can also be found in patients with mild neurological deficits. Respiratory disturbances in stroke victims can be explained only in part by topography and extension of acute brain damage.\n          <\/jats:p>","DOI":"10.1161\/01.str.28.9.1765","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1765-1772","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":124,"title":["Sleep-Disordered Breathing in Patients With Acute Supra- and Infratentorial Strokes"],"prefix":"10.1161","volume":"28","author":[{"given":"Claudio","family":"Bassetti","sequence":"first","affiliation":[{"name":"From the Departments of Neurology (C.B., M.S.A.) and Neuroradiology (D.Q.), University of Michigan Hospitals, Ann Arbor, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Aldrich","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (C.B., M.S.A.) and Neuroradiology (D.Q.), University of Michigan Hospitals, Ann Arbor, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Quint","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (C.B., M.S.A.) and Neuroradiology (D.Q.), University of Michigan Hospitals, Ann Arbor, Mich."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197707142970206"},{"key":"e_1_3_2_2_2","unstructured":"Simon RP. 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