{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T03:10:35Z","timestamp":1774062635193,"version":"3.50.1"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1998,10]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014There is scant information available on the incidence of transient ischemic attack (TIA) in a defined population. This study defines incidence rates of first TIA and subtypes of TIA during 1985\u20131989 and compares the incidence to that obtained from a 1960\u20131972 cohort study.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014Medical records of all residents of Rochester with potential diagnosis of TIA during 1985\u20131989 were screened to determine whether the case met the criteria for TIA. All available data were used to determine the vascular distribution of the TIA. Average annual age- and sex-adjusted incidence rates were calculated for 1985\u20131989, and results were compared with incidence rates determined in a Rochester-based 1960\u20131972 cohort study.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014Two hundred two cases of first TIA or amaurosis fugax occurred among Rochester residents during 1985\u20131989. The age- and sex-adjusted incidence rate for any TIA was 68\/100 000 population. Incidence of amaurosis fugax was 13\/100 000; anterior circulation (cerebral) TIA, 38\/100 000; and vertebrobasilar distribution TIA, 14\/100 000. Rates were similar to those determined from a 1960\u20131972 cohort study.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014The incidence rate of TIA is 41% that of stroke incidence. TIA incidence in Rochester, Minn, is higher than has been previously reported for other sites throughout the world. Although comparison with prior time periods is difficult because of ascertainment issues, it appears that there has been no significant change in TIA incidence since the decade of the 1960s or earlier. This suggests that the most common mechanism for TIA (atherosclerosis) has not changed in prevalence, nor have risk factors leading to this mechanism.\n          <\/jats:p>","DOI":"10.1161\/01.str.29.10.2109","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2109-2113","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":79,"title":["Incidence of Transient Ischemic Attack in Rochester, Minnesota, 1985\u20131989"],"prefix":"10.1161","volume":"29","author":[{"suffix":"Jr","given":"Robert D.","family":"Brown","sequence":"first","affiliation":[{"name":"From the Division of Cerebrovascular Diseases and Department of Neurology (R.D.B., G.W.P., D.O.W., J.P.W.), and Department of Health Sciences Research (W.M.O\u2019F., D.O.W., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George W.","family":"Petty","sequence":"additional","affiliation":[{"name":"From the Division of Cerebrovascular Diseases and Department of Neurology (R.D.B., G.W.P., D.O.W., J.P.W.), and Department of Health Sciences Research (W.M.O\u2019F., D.O.W., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Michael","family":"O\u2019Fallon","sequence":"additional","affiliation":[{"name":"From the Division of Cerebrovascular Diseases and Department of Neurology (R.D.B., G.W.P., D.O.W., J.P.W.), and Department of Health Sciences Research (W.M.O\u2019F., D.O.W., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David O.","family":"Wiebers","sequence":"additional","affiliation":[{"name":"From the Division of Cerebrovascular Diseases and Department of Neurology (R.D.B., G.W.P., D.O.W., J.P.W.), and Department of Health Sciences Research (W.M.O\u2019F., D.O.W., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack P.","family":"Whisnant","sequence":"additional","affiliation":[{"name":"From the Division of Cerebrovascular Diseases and Department of Neurology (R.D.B., G.W.P., D.O.W., J.P.W.), and Department of Health Sciences Research (W.M.O\u2019F., D.O.W., J.P.W.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","first-page":"194","volume":"48","year":"1973","unstructured":"Whisnant JP, Matsumoto N, Elveback LR. Transient cerebral ischemic attacks in a community. Mayo Clin Proc. 1973;48:194\u2013198.","journal-title":"Mayo Clin Proc"},{"key":"e_1_3_2_2_2","first-page":"117","volume":"52","year":"1977","unstructured":"Cartlidge NEF, Whisnant JP, Elveback LR. Carotid and vertebral-basilar transient cerebral ischemic attacks. 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Transient ischemic attacks in a community. JAMA. 1969;8:1428\u20131434.","journal-title":"JAMA"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.4.6.980"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.18.2.3564095"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220290013003"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.19.2.3344535"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410220307"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican1081-54"},{"key":"e_1_3_2_19_2","unstructured":"Bergstrahl EJ Offord KP Chu C-P Beard CM O\u2019Fallon WM. Calculating Incidence Prevalence and Mortality Rates for Olmsted County Minnesota Residents: An Update. Rochester Minn: Mayo Clinic Section of Biostatistics; 1992. Technical Report Series No. 49."},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","unstructured":"McCullagh P Nelder JA. Generalized Linear Models. New York NY: Chapman and Hall; 1983:127\u2013147.","DOI":"10.1007\/978-1-4899-3244-0_6"},{"key":"e_1_3_2_21_2","unstructured":"Whisnant JP. Natural history of transient ischemic attack and ischemic stroke. In: Whisnant JP ed. Stroke: Populations Cohorts and Clinical Trials. Oxford England: Butterworth-Heinemann; 1993:135\u2013153."},{"key":"e_1_3_2_22_2","unstructured":"Whisnant JP Wiebers DO. Clinical epidemiology of transient cerebral ischemic attacks in the anterior and posterior cerebral circulation. In: Meyer FB ed. Sundt\u2019s Occlusive Cerebrovascular Disease: Diagnosis And Surgical Management. New York NY: WB Saunders Co; 1994:71\u201377."},{"key":"e_1_3_2_23_2","first-page":"373","volume":"27","year":"1996","unstructured":"Brown RD Jr, Whisnant JP, Sicks J, O\u2019Fallon WM, Wiebers DO. 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