{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:12:52Z","timestamp":1790179972539,"version":"4.1.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1998,12]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014Internal carotid artery dissection (ICAD) is a frequent cause of ischemic stroke in young patients. Whether cerebral ischemia is of embolic or hemodynamic origin remains to be determined. Heparin is often administered in ICAD; however, a drug trial can hardly be conducted because of the low recurrence rate after the acute stage. Therefore, the best therapeutic approach should be determined on the basis of the presumed mechanism of cerebral ischemia. One way to approach the mechanism of stroke in ICAD is to determine stroke patterns. We postulated that most cortical and large subcortical infarcts (\u226515 mm) are of embolic origin and that small subcortical infarcts (&lt;15 mm) and junctional infarcts are not. The aim of our study was to determine the stroke patterns in 40 consecutive patients with ICAD.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014The patients (26 women and 14 men; mean age, 42.8 years) had a total of 65 ICADs. Seventeen patients were free of any vascular risk factor. CT scans, MRI scans, and angiographic features were analyzed by observers who were blinded to the clinical findings.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014We found 34 cortical infarcts, 25 large subcortical infarcts, 1 small subcortical infarct, and 5 junctional infarcts.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014Most infarcts related to ICAD are cortical infarcts or large subcortical infarcts; small subcortical infarcts and junctional infarcts are infrequent. Therefore, these findings suggest that most infarcts occurring in carotid artery dissection (CAD) are probably embolic rather than hemodynamic in origin. According to this presumed mechanism, anticoagulation seems a logical treatment at the early stage of CAD.\n          <\/jats:p>","DOI":"10.1161\/01.str.29.12.2646","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2646-2648","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":231,"title":["Stroke Patterns of Internal Carotid Artery Dissection in 40 Patients"],"prefix":"10.1161","volume":"29","author":[{"given":"Christian","family":"Lucas","sequence":"first","affiliation":[{"name":"From the Departments of Neurology and Neuroradiology, Lille (C.L., D.D.) and Besanc\u0327on (T.M., L.T., D.C.) University Hospitals, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Moulin","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology and Neuroradiology, Lille (C.L., D.D.) and Besanc\u0327on (T.M., L.T., D.C.) University Hospitals, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Deplanque","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology and Neuroradiology, Lille (C.L., D.D.) and Besanc\u0327on (T.M., L.T., D.C.) University Hospitals, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Tatu","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology and Neuroradiology, Lille (C.L., D.D.) and Besanc\u0327on (T.M., L.T., D.C.) University Hospitals, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Chavot","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology and Neuroradiology, Lille (C.L., D.D.) and Besanc\u0327on (T.M., L.T., D.C.) University Hospitals, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30236-6"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1987.00520170009012"},{"key":"e_1_3_2_3_2","unstructured":"Saver JL Easter JD Hart RG. Dissections and trauma of cervicocerebral arteries. In: Barnett HJM Mohr JP Stein BM Yatsu FD eds. Stroke: Pathophysiology Diagnosis and Management. New York NY: Churchill Livingstone Inc; 1992:671\u2013688."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00313032"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00868406"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000107817"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1988.0801001.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1983.04050030032005"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.3.373"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","unstructured":"Bogousslavsky J. Topographic patterns of cerebral infarcts. Cerebrovasc Dis. 1991;1(suppl 1):61\u201368.","DOI":"10.1159\/000108899"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000117396"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000108861"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.4.507"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000117001"}],"container-title":["Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.29.12.2646","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T22:40:36Z","timestamp":1715553636000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.STR.29.12.2646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,12]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1998,12]]}},"alternative-id":["10.1161\/01.STR.29.12.2646"],"URL":"https:\/\/doi.org\/10.1161\/01.str.29.12.2646","relation":{},"ISSN":["0039-2499","1524-4628"],"issn-type":[{"value":"0039-2499","type":"print"},{"value":"1524-4628","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,12]]},"assertion":[{"value":"1998-04-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-09-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1998-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}