{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T04:33:56Z","timestamp":1792557236098,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1999,11]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014Proper assessment of extracranial internal carotid artery high-grade stenosis and occlusion by extracranial color-coded duplex sonography (ECCD) is occasionally made difficult by shadowing, an unfavorable insonation angle, low flow velocity or volume, or a deep insonation depth. In these cases, echocontrast could be helpful to quantify the degree of stenosis and to diagnose occlusion.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014We investigated 17 arteries with poor precontrast investigation conditions and suspected high-grade stenosis or occlusion by contrast-enhanced ECCD.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014Compared with the precontrast scans, echocontrast allowed for significantly more segments to be evaluated by pulsed Doppler sonography (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001) and for longer lumen segments to be displayed on color mode (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001). Because it was now possible to place the sample volume right into the jet of the stenosis, the maximal flow velocity registered increased in all patients with stenosis.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014Echocontrast-enhanced ECCD of the carotid arteries is helpful for stenosis classification in a small group of preselected patients with poor original examination conditions.\n          <\/jats:p>","DOI":"10.1161\/01.str.30.11.2302","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2302-2306","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":39,"title":["Echocontrast-Enhanced Ultrasound of Extracranial Internal Carotid Artery High-Grade Stenosis and Occlusion"],"prefix":"10.1161","volume":"30","author":[{"given":"Dirk W.","family":"Droste","sequence":"first","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmus","family":"Ju\u0308rgens","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius G.","family":"Nabavi","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Schuierer","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sepp","family":"Weber","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Bernd","family":"Ringelstein","sequence":"additional","affiliation":[{"name":"From the Departments of Neurology (D.W.D, R.J., D.G.N., E.B.R.) and Radiology (G.S.), University of Mu\u0308nster; and Schering AG (S.W.), Berlin, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","unstructured":"von Reutern G-M B\u00fcdingen HJ. Ultraschalldiagnostik der hirnversorgenden Arterien. 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