{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:14:52Z","timestamp":1791180892794,"version":"4.1.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[1999,4]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014Fractures are a serious complication after stroke, and the risk of hip fractures among stroke patients is increased 2 to 4 times versus a reference population. Fractures after stroke are probably caused by the development of hemiosteoporosis and the high incidence of accidental falls. The aim of this study was to investigate the development of hemiosteoporosis in relation to other changes in body composition during the first year after severe stroke.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014The study included 24 patients with extensive paresis after stroke. Bone mineral content (BMC) and fat and lean mass were assessed 1, 4, 7, and 12 months after stroke onset by a dual-energy x-ray absorptiometer.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014The loss of total body BMC was significant during the first year after stroke (\u20131.6%;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.05), but there were no significant changes in total lean or fat mass. At inclusion, there were no significant differences between sides in lean or fat mass or BMC, but during follow-up, BMC of the affected side decreased significantly compared with the same side at inclusion (\u20137.5%;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.01). Side differences in fat mass became significant between legs (9.3%;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001) and whole sides (4.8%;\n            <jats:italic>P<\/jats:italic>\n            &lt;0.01). There were only minor side changes in lean mass. Loss of BMC was independent of weight changes.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014During the first year after severe stroke, patients developed pronounced hemiosteoporosis. This was not associated with general changes in lean or fat mass. The development of hemiosteoporosis was independent of weight changes after stroke.\n          <\/jats:p>","DOI":"10.1161\/01.str.30.4.755","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:10:52Z","timestamp":1308341452000},"page":"755-760","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":72,"title":["Hemiosteoporosis After Severe Stroke, Independent of Changes in Body Composition and Weight"],"prefix":"10.1161","volume":"30","author":[{"given":"A.","family":"Ramnemark","sequence":"first","affiliation":[{"name":"From the Department of Geriatric Medicine (A.R., L.N., Y.G.), Sports Medicine Unit, Department of Orthopaedics (R.L.), and Department of Medicine (T.O.) Umea\u030a University, Umea\u030a, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Nyberg","sequence":"additional","affiliation":[{"name":"From the Department of Geriatric Medicine (A.R., L.N., Y.G.), Sports Medicine Unit, Department of Orthopaedics (R.L.), and Department of Medicine (T.O.) Umea\u030a University, Umea\u030a, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Lorentzon","sequence":"additional","affiliation":[{"name":"From the Department of Geriatric Medicine (A.R., L.N., Y.G.), Sports Medicine Unit, Department of Orthopaedics (R.L.), and Department of Medicine (T.O.) Umea\u030a University, Umea\u030a, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Olsson","sequence":"additional","affiliation":[{"name":"From the Department of Geriatric Medicine (A.R., L.N., Y.G.), Sports Medicine Unit, Department of Orthopaedics (R.L.), and Department of Medicine (T.O.) Umea\u030a University, Umea\u030a, Sweden."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Gustafson","sequence":"additional","affiliation":[{"name":"From the Department of Geriatric Medicine (A.R., L.N., Y.G.), Sports Medicine Unit, Department of Orthopaedics (R.L.), and Department of Medicine (T.O.) 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