{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T11:14:54Z","timestamp":1774437294724,"version":"3.50.1"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2000,12]]},"abstract":"\n Background and Purpose<\/jats:italic>\n \u2014We sought to characterize the subtypes of stroke associated with pregnancy and the puerperium, with emphasis on timing, etiology, risk factors, and outcome.\n <\/jats:p>\n \n Methods<\/jats:italic>\n \u2014We conducted a retrospective analysis of patients admitted to the Toronto Hospital between January 1, 1980, and June 30, 1997, with a diagnosis of stroke during pregnancy or within 6 weeks postpartum. Strokes were classified as ischemic (arterial or venous) or hemorrhagic (subarachnoid or intracerebral). All patients were investigated with at least a CT scan of the head, and most had MRI and\/or cerebral angiography.\n <\/jats:p>\n \n Results<\/jats:italic>\n \u2014Of approximately 50 700 admissions for delivery, 34 patients with a diagnosis of stroke were identified (21 infarctions and 13 hemorrhages). Of patients with infarction, 13 were arterial and 8 were venous. Nine of 13 arterial events occurred in the third trimester or puerperium. Seven of 8 venous occlusions occurred postpartum. An etiologic diagnosis was made in 7 of 13 patients with arterial territory infarction, including cardiac emboli, coagulopathies, and carotid artery dissection. Of patients with hemorrhage, 7 were subarachnoid and 6 were intracerebral. The etiology was identified in 10 patients: 3 were due to ruptured aneurysms, 5 were associated with arteriovenous malformations, and 2 were associated with disseminated intravascular coagulation. All patients with infarction survived, but 3 patients with hemorrhage died.\n <\/jats:p>\n \n Conclusions<\/jats:italic>\n \u2014The majority of strokes associated with pregnancy were arterial occlusions. Most presented during the third trimester and puerperium.\n <\/jats:p>","DOI":"10.1161\/01.str.31.12.2948","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2948-2951","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":219,"title":["Stroke and Pregnancy"],"prefix":"10.1161","volume":"31","author":[{"given":"Cheryl","family":"Jaigobin","sequence":"first","affiliation":[{"name":"From the Toronto Western Hospital, University Health Network, Division of Neurology, University of Toronto (Ontario, Canada)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank L.","family":"Silver","sequence":"additional","affiliation":[{"name":"From the Toronto Western Hospital, University Health Network, Division of Neurology, University of Toronto (Ontario, Canada)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","unstructured":"Barnett HJM. Stroke in women. Can J Cardiol. 1990;6(suppl B):11B\u201317B."},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000176898"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30236-6"},{"key":"e_1_3_1_4_2","first-page":"91","volume":"72","year":"1988","unstructured":"Rochat RW, Koonin LM, Atrash HK, Jewett JF. Maternal mortality in the United States: report from the Maternal Mortality Collaborative. 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