{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:09:22Z","timestamp":1767650962820},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2000,4]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014Percutaneous transluminal angioplasty combined with vascular stenting is currently being assessed in the treatment of patients with symptomatic, severe carotid stenosis. The immediate cerebral hemodynamic effects resulting from stenting are not fully understood. This article describes a novel finding: abnormal leptomeningeal enhancement after stenting shown by MRI.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014Fourteen patients with symptomatic severe carotid bifurcation stenosis underwent MRI within 4 hours before and within 3 hours after attempted carotid stenting. Twelve patients were successfully stented. Part of the MR investigation consisted of the acquisition of T1-weighted images before and after administration of the contrast agent Gd-DTPA, both before and after the procedure.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014All 12 patients who underwent successful stenting did not have abnormal enhancement of the leptomeninges before stenting but developed unilateral enhancement following intervention but before the second injection of contrast agent. No contrast enhancement was detected in the 2 patients who had the angiographic procedure but were not stented.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014These findings suggest that abnormal changes to the leptomeningeal vasculature occur during carotid stenting which are not associated with sudden development of neurological symptoms. The anatomic distribution of the enhancement suggests that it is a consequence of the sudden change in brain hemodynamics secondary to the improvement in carotid flow after stenting.\n          <\/jats:p>","DOI":"10.1161\/01.str.31.4.848","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:10:52Z","timestamp":1308341452000},"page":"848-851","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":32,"title":["Unilateral Leptomeningeal Enhancement After Carotid Stent Insertion Detected by Magnetic Resonance Imaging"],"prefix":"10.1161","volume":"31","author":[{"given":"Iain D.","family":"Wilkinson","sequence":"first","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel","family":"Hoggard","sequence":"additional","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor J.","family":"Cleveland","sequence":"additional","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Gaines","sequence":"additional","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham S.","family":"Venables","sequence":"additional","affiliation":[{"name":"From the Section of Academic Radiology, University of Sheffield (I.D.W., P.D.G., N.H.); Sheffield Vascular Institute, Northern General Hospital (T.J.C., P.A.G.); and Department of Neurology, Royal Hallamshire Hospital (G.S.V.), Sheffield, England."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108153250701"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92916-P"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)09292-1"},{"key":"e_1_3_2_4_2","first-page":"262","volume":"66","year":"1999","unstructured":"Brown MM, for the Carotid and Vertebral Artery Transluminal Angioplasty investigation group. 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