{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:31:18Z","timestamp":1772109078476,"version":"3.50.1"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014Previous studies have shown that the volume of intracerebral hemorrhage and Glasgow Coma Score (GCS) on admission are powerful predictors of 30-day mortality. However, the significance of hydrocephalus associated with deep cerebral hemorrhage has not been studied extensively. The purpose of this study was to determine the prognostic indicators of 30-day mortality in patients with deep cerebral hemorrhage.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014We studied 100 consecutive patients with deep cerebral hemorrhage between 1994 and 1998. Deep cerebral hemorrhage was divided into 2 groups: putaminal hemorrhage (lateral group) and thalamic and caudate hemorrhage (medial group). Univariate and multivariate logistic regression analyses were performed to determine independent prognostic indicators of 30-day mortality.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014Hydrocephalus was present in 40 of the 100 patients. The 30-day mortality was 29%, and hydrocephalus was present in 76% of those who died. Multivariate analyses showed 2 independent prognostic indicators of 30-day mortality for putaminal hemorrhage: GCS \u22648 (\n            <jats:italic>P<\/jats:italic>\n            =0.002, odds ratio [OR] 37.7, CI 3.6 to 396.9) and hydrocephalus (\n            <jats:italic>P<\/jats:italic>\n            =0.005, OR 27.4, CI 2.7 to 282.6). However, only GCS \u22648 (\n            <jats:italic>P<\/jats:italic>\n            =0.0002, OR 16.5, CI 3.7 to 73.4) was predictive of 30-day mortality for thalamic and caudate hemorrhage. This model (GCS \u22648 and hydrocephalus) has a sensitivity of 57% and a specificity of 91% for predicting 30-day mortality for putaminal hemorrhage. When both attributes were present in putaminal hemorrhage (GCS \u22648 and hydrocephalus), 1 (11%) of 9 patients survived, and when both attributes were missing 28 (100%) of 28 patients survived.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014Obstructive hydrocephalus on admission in a comatose patient with a putaminal hemorrhage predicts 30-day mortality.\n          <\/jats:p>","DOI":"10.1161\/01.str.31.9.2157","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"2157-2162","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":64,"title":["Hydrocephalus Is a Determinant of Early Mortality in Putaminal Hemorrhage"],"prefix":"10.1161","volume":"31","author":[{"given":"Thanh G.","family":"Phan","sequence":"first","affiliation":[{"name":"From the Department of Neurology (T.G.P., M.K., E.F.M.W.) and the Department of Health Science Research (Section of Biostatistics) (R.A.V.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merian","family":"Koh","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (T.G.P., M.K., E.F.M.W.) and the Department of Health Science Research (Section of Biostatistics) (R.A.V.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Vierkant","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (T.G.P., M.K., E.F.M.W.) and the Department of Health Science Research (Section of Biostatistics) (R.A.V.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eelco F.M.","family":"Wijdicks","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (T.G.P., M.K., E.F.M.W.) and the Department of Health Science Research (Section of Biostatistics) (R.A.V.), Mayo Clinic and Mayo Foundation, Rochester, Minn."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.7.8322400"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.29.7.1352"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.29.9.1799"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.27.8.1304"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.26.6.964"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.22.5.2028484"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.98.14.1376"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.28.7.1396"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.24.9.8362433"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.29.6.1160"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240213"},{"key":"e_1_3_1_12_2","doi-asserted-by":"crossref","unstructured":"Schwarz S Hafner K Aschoff A Schwab S. 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