{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:51:55Z","timestamp":1790628715622,"version":"4.1.0"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p>\n                    <jats:italic>Background and Purpose<\/jats:italic>\n                    \u2014Smoking, hypertension, alcohol consumption, autosomal dominant polycystic kidney disease (ADPKD), and positive family history for subarachnoid hemorrhage (SAH) are well-known risk factors for SAH. For effective prevention, knowledge about the contribution of these risk factors to the overall occurrence of SAH in the general population is pivotal. We therefore investigated the population attributable risks of the risk factors for SAH.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods<\/jats:italic>\n                    \u2014We retrieved the relative risk and prevalence of established risk factors for SAH from the literature and calculated the population attributable risks of these risk factors.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    \u2014Drinking alcohol 100 to 299 g\/wk accounted for 11% of the cases of SAH, drinking alcohol \u2265300 g\/wk accounted for 21%, and smoking accounted for 20%. An additional 17% of the cases could be attributed to hypertension, 11% to a positive family history for SAH, and 0.3% to ADPKD.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    \u2014Screening and preventive treatment of patients with familial preponderance of SAH alone will cause a modest reduction of the incidence of SAH in the general population. Further reduction can be achieved by reducing the prevalence of the modifiable risk factors alcohol consumption, smoking, and hypertension.\n                  <\/jats:p>","DOI":"10.1161\/01.str.32.5.1173","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T16:10:52Z","timestamp":1308327052000},"page":"1173-1175","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":93,"title":["Attributable Risk of Common and Rare Determinants of Subarachnoid Hemorrhage"],"prefix":"10.1161","volume":"32","author":[{"given":"Ynte M.","family":"Ruigrok","sequence":"first","affiliation":[{"name":"From the Department of Neurology (Y.M.R., G.J.E.R.) and Julius Center for General Practice and Patient Oriented Research (E.B.), University Medical Center Utrecht (Netherlands)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Buskens","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Y.M.R., G.J.E.R.) and Julius Center for General Practice and Patient Oriented Research (E.B.), University Medical Center Utrecht (Netherlands)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrie\u0308l J. E.","family":"Rinkel","sequence":"additional","affiliation":[{"name":"From the Department of Neurology (Y.M.R., G.J.E.R.) and Julius Center for General Practice and Patient Oriented Research (E.B.), University Medical Center Utrecht (Netherlands)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.27.4.625"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.28.3.660"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.27.3.544"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1681\/ASN.V3188","volume":"3","year":"1992","unstructured":"Schievink WI, Torres VE, Piepgras DG, Wiebers DO. Saccular intracranial aneurysms in autosomal dominant polycystic kidney disease. 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