{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:44:28Z","timestamp":1773384268215,"version":"3.50.1"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2001,6]]},"abstract":"<jats:p>\n            <jats:italic>Background and Purpose<\/jats:italic>\n            \u2014We sought to perform a large, prospective, multicenter, blinded study comparing power transcranial color duplex sonography (power TCDS) with intra-arterial digital subtraction angiography (IADSA) in the detection of intracranial aneurysms.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Methods<\/jats:italic>\n            \u2014Contemporaneous TCDS and IADSA examinations were performed in 171 subjects with suspected intracranial aneurysm. Via the temporal bone window, a 2-dimensional hand-held noncontrast transcranial duplex ultrasound imaging system was used operating in power and spectral modes. Sonographers were blinded to clinical history and results of brain CT and IADSA.\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Results<\/jats:italic>\n            \u2014We found that 157 subjects (92%) had an adequate bone window. Sensitivity per patient was 0.78 (95% CI, 0.66 to 0.87) and 0.46 (95% CI, 0.36 to 0.56) for any anterior circulation aneurysms. Sensitivity was 0.35 (95% CI, 0.24 to 0.46) for aneurysms \u22645 mm and 0.81 (95% CI, 0.62 to 0.94) for aneurysms &gt;5 mm. Accuracy was lower for aneurysms on the cavernous and terminal internal carotid arteries, including posterior communicating artery origin (0.71; 95% CI, 0.63 to 0.79), than for those on the anterior (0.82; 95% CI, 0.74 to 0.89) or the middle cerebral arteries (0.79; 95% CI, 0.71 to 0.86).\n          <\/jats:p>\n          <jats:p>\n            <jats:italic>Conclusions<\/jats:italic>\n            \u2014Power TCDS is a promising, inexpensive, noninvasive test for anterior circulation intracranial aneurysms but is less sensitive per aneurysm than alternatives such as CT angiography or MR angiography. Sensitivity is poor for aneurysms \u22645 mm in diameter. The internal carotid artery is the most difficult segment to interpret.\n          <\/jats:p>","DOI":"10.1161\/01.str.32.6.1291","type":"journal-article","created":{"date-parts":[[2011,6,17]],"date-time":"2011-06-17T20:08:03Z","timestamp":1308341283000},"page":"1291-1297","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Power Transcranial Doppler Ultrasound in the Detection of Intracranial Aneurysms"],"prefix":"10.1161","volume":"32","author":[{"given":"Philip M.","family":"White","sequence":"first","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna M.","family":"Wardlaw","sequence":"additional","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyn","family":"Teasdale","sequence":"additional","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Sloss","sequence":"additional","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Cannon","sequence":"additional","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Easton","sequence":"additional","affiliation":[{"name":"From the Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow (P.M.W., E.T., S.S.); Department of Clinical Neurosciences, Western General Hospital, Edinburgh (P.M.W., J.M.W., J.C., V.E.); and Department of Community Health Sciences, University of Edinburgh (V.E.) (UK)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.88.4.0679"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.208.2.9680571"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(98)00015-9"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.30.2.317"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.2.205"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.217.2.r00nv06361"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199209000-00006"},{"key":"e_1_3_2_8_2","first-page":"497","volume":"12","year":"1991","unstructured":"Tsuchiya T, Yasaka M, Yamaguchi T, Kimura K, Omae T. Imaging of the basal cerebral arteries and measurement of blood velocity in adults using transcranial real-time color flow Doppler sonography. 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