{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:54:56Z","timestamp":1791294896864,"version":"4.1.0"},"reference-count":162,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["ATVB"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:p>Thrombotic complications of vascular disease are the leading cause of morbidity and mortality in most industrialized countries. Despite this, safe and effective drugs targeting these complications are limited, especially in the chronic setting. This is because of the complexity of thrombosis in both arteries and veins, which is becoming increasingly evident as numerous factors are now known to affect the fate of a forming thrombus. To fully characterize thrombus formation in these settings, in vivo models are necessary to study the various components and intricate interactions that are involved. Genetic manipulations in mice are greatly facilitating the dissection of relevant pro- and antithrombotic influences. Standardized models for the study of thrombosis in mice as well as evolving techniques that allow imaging of molecular events during thrombus formation are now available. This review will highlight some of the recent developments in the field of thrombosis using mouse models and how these studies are expanding our knowledge of thrombotic disease.<\/jats:p>","DOI":"10.1161\/atvbaha.107.142810","type":"journal-article","created":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T01:11:51Z","timestamp":1183079511000},"page":"2079-2093","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":169,"title":["Murine Models of Vascular Thrombosis"],"prefix":"10.1161","volume":"27","author":[{"given":"Randal J.","family":"Westrick","sequence":"first","affiliation":[{"name":"From the Departments of Human Genetics (R.W.), Internal Medicine (M.W.), and the Division of Cardiology (D.E.), University of Michigan Medical Center, Ann Arbor."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Winn","sequence":"additional","affiliation":[{"name":"From the Departments of Human Genetics (R.W.), Internal Medicine (M.W.), and the Division of Cardiology (D.E.), University of Michigan Medical Center, Ann Arbor."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel T.","family":"Eitzman","sequence":"additional","affiliation":[{"name":"From the Departments of Human Genetics (R.W.), Internal Medicine (M.W.), and the Division of Cardiology (D.E.), University of Michigan Medical Center, Ann Arbor."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.06.072"},{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.113.22.f85"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00059.2005"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.101.13.1546"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000107402.79771.fc"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000229883.72010.e4"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.174516"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.172860"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199905203402007"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.8.2817"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01461.x"},{"key":"e_1_3_3_12_2","unstructured":"Virchow RLK Thrombosis and Emboli. Canton Mass: Science History Publications\/USA; 1846."},{"key":"e_1_3_3_13_2","first-page":"66","volume":"74","year":"1944","unstructured":"Reimann-Hunziker G. Uber experimentelle Thrombose und ihre Behandlung mit Heparin. Schweizerische Medizinische Wochenschrift. 1944; 74: 66\u201369.","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"e_1_3_3_14_2","first-page":"165","volume":"1","year":"1972","unstructured":"Didisheim P. Animal models useful in the study of thrombosis and antithrombotic agents. Prog Hemost Thromb. 1972; 1: 165\u2013197.","journal-title":"Prog Hemost Thromb"},{"key":"e_1_3_3_15_2","first-page":"502","volume":"10","year":"1969","unstructured":"Arfors KE, Dhall DP, Engeset J, Hint H, Matheson NA, Tangen O. In vivo quantitation of platelet activity using biolaser-induced endothelial injury. Bibl Anat. 1969; 10: 502\u2013506.","journal-title":"Bibl Anat"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64117-X"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.16.9524"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.16.7450"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm782"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.643908"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613739"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(90)90106-M"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2005.09.004"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.97.10.1002"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2004.07.009"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.4.1055"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01639.x"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01703.x"},{"key":"e_1_3_3_29_2","doi-asserted-by":"crossref","unstructured":"Wang X Smith PL Hsu MY Tamasi JA Bird E Schumacher WA Deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI) protected mice from ferric chloride-induced vena cava thrombosis. J Thromb Thrombolysis. 2006.","DOI":"10.1007\/s11239-006-9009-4"},{"key":"e_1_3_3_30_2","first-page":"57","volume":"225","year":"1983","unstructured":"DiMinno G, Silver MJ. Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol. J Pharmacol Exp Ther. 1983; 225: 57\u201360.","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2005.12.010"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613582"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00108-4"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700171"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.5.3388"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.73.5.792"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.20.2.335"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.19.12.3014"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-02-0122"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118307"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000085568.13915.1e"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(90)91462-G"},{"key":"e_1_3_3_43_2","first-page":"2357","volume":"32","year":"1991","unstructured":"Wilson CA, Hatchell DL. Photodynamic retinal vascular thrombosis. Rate and duration of vascular occlusion. Invest Ophthalmol Vis Sci. 1991; 32: 2357\u20132365.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410170513"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V95.2.577"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(96)00131-4"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(97)00101-6"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1614532"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1612950"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.13.1706"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.13.4212"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01551.x"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.103.4.576"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.03.074"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5262.685"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1161\/atv91.14.1.8274468"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.20.7.1831"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.103.25.3044"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.13.4222"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.120081897"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000017361.39256.82"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000183884.06371.52"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2005.12.037"},{"key":"e_1_3_3_64_2","first-page":"6.","volume":"6","year":"2006","unstructured":"Hoover-Plow JL, Shchurin A, Hart E, Sha J, Singer JB, Hill AE, Nadeau JH. Genetic Background Determines Response to Hemostasis and Thrombosis. BMC Blood Disord. 2006; 6: 6.","journal-title":"BMC Blood Disord"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1093139"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000229658.76797.30"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200301000-00034"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-03-0935"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-06-2225"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.95.3.594"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2003.00482.x"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0213432"},{"key":"e_1_3_3_73_2","doi-asserted-by":"crossref","unstructured":"Silver L. Mouse Genetics Concepts and Applications. New York: Oxford University Press Inc.; 1995.","DOI":"10.1093\/oso\/9780195075540.001.0001"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.20.6.1425"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1054\/npep.2002.0905"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36699"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-03-0945"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.022608799"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000206442.86238.39"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-005-0063-6"},{"key":"e_1_3_3_81_2","first-page":"308","volume":"80","year":"1965","unstructured":"Fry RJ, Hamilton KH, Lisco H. Thrombi in the left atrium of the heart in mice. Arch Pathol. 1965; 80: 308\u2013313.","journal-title":"Arch Pathol"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1002\/gene.1030"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.193.6.741"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.08.134"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.69.3.426-439.2005"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-004-2379-z"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.242474199"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-06-2272"},{"key":"e_1_3_3_89_2","doi-asserted-by":"crossref","unstructured":"Eitzman DaW RJ. Vascular Photochemical Injury in the Mouse. In: Rogers DISaC ed. Contemporary Cardiology: Vascular Disease and Injury: Preclinical Research. Totowa NJ: Humana Press Inc.; 2000.","DOI":"10.1007\/978-1-59259-003-2_8"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000252068.89775.ee"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000097766.36623.df"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1038\/12447"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0302-247"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-09-3687"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01236.x"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000216282.58291.c6"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050664"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01849.x"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1081\/RRS-200040324"},{"key":"e_1_3_3_100_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1470"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.12.071"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI22973"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01217.x"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI9896"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-12-4835"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-11-3994"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-05-2005"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.22.3.499"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1038\/84667"},{"key":"e_1_3_3_110_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1323"},{"key":"e_1_3_3_111_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000163184.02484.69"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030144"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20021868"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.193.4.459"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI8399"},{"key":"e_1_3_3_116_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.2.368"},{"key":"e_1_3_3_117_2","doi-asserted-by":"publisher","DOI":"10.1089\/1523086041361677"},{"key":"e_1_3_3_118_2","doi-asserted-by":"publisher","DOI":"10.1038\/41780"},{"key":"e_1_3_3_119_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1512"},{"key":"e_1_3_3_120_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.21.9.1531"},{"key":"e_1_3_3_121_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-003-0416-9"},{"key":"e_1_3_3_122_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V93.6.1825.406k37_1825_1830"},{"key":"e_1_3_3_123_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20051732"},{"key":"e_1_3_3_124_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000173306.47722.ec"},{"key":"e_1_3_3_125_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-02-005991"},{"key":"e_1_3_3_126_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000160854.75779.e8"},{"key":"e_1_3_3_127_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000043901.45141.D4"},{"key":"e_1_3_3_128_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001721-200209000-00004"},{"key":"e_1_3_3_129_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000194076.84568.81"},{"key":"e_1_3_3_130_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-07-2765"},{"key":"e_1_3_3_131_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1538-7836.2003.00003.x"},{"key":"e_1_3_3_132_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.104.10.1176"},{"key":"e_1_3_3_133_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000219687.71607.f7"},{"key":"e_1_3_3_134_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.12.091"},{"key":"e_1_3_3_135_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI25074"},{"key":"e_1_3_3_136_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(98)00133-6"},{"key":"e_1_3_3_137_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000015502.97828.93"},{"key":"e_1_3_3_138_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(00)00515-3"},{"key":"e_1_3_3_139_2","doi-asserted-by":"publisher","DOI":"10.1161\/atvb.20.12.2587"},{"key":"e_1_3_3_140_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000014587.66321.b4"},{"key":"e_1_3_3_141_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.915"},{"key":"e_1_3_3_142_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000036081.01231.16"},{"key":"e_1_3_3_143_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000158435.98035.8d"},{"key":"e_1_3_3_144_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-10-3721"},{"key":"e_1_3_3_145_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb03515.x"},{"key":"e_1_3_3_146_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.13.6922"},{"key":"e_1_3_3_147_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI26007"},{"key":"e_1_3_3_148_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-09-0635"},{"key":"e_1_3_3_149_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1023"},{"key":"e_1_3_3_150_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH02-09-0093"},{"key":"e_1_3_3_151_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-04-0206"},{"key":"e_1_3_3_152_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.0000232317.84122.0c"},{"key":"e_1_3_3_153_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(02)02449-4"},{"key":"e_1_3_3_154_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(03)00114-0"},{"key":"e_1_3_3_155_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613871"},{"key":"e_1_3_3_156_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-200202000-00015"},{"key":"e_1_3_3_157_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-200012000-00013"},{"key":"e_1_3_3_158_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-02-0598"},{"key":"e_1_3_3_159_2","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.105.084673"},{"key":"e_1_3_3_160_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH06-02-0118"},{"key":"e_1_3_3_161_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.2000.00704.x"},{"key":"e_1_3_3_162_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2005.09.006"}],"container-title":["Arteriosclerosis, Thrombosis, and Vascular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/ATVBAHA.107.142810","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,17]],"date-time":"2025-01-17T23:48:48Z","timestamp":1737157728000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/ATVBAHA.107.142810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":162,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1161\/ATVBAHA.107.142810"],"URL":"https:\/\/doi.org\/10.1161\/atvbaha.107.142810","relation":{},"ISSN":["1079-5642","1524-4636"],"issn-type":[{"value":"1079-5642","type":"print"},{"value":"1524-4636","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,10]]},"assertion":[{"value":"2007-06-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}