{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:51:03Z","timestamp":1790830263448,"version":"4.1.0"},"reference-count":59,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["ATVB"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec>\n            <jats:title>Objective\u2014<\/jats:title>\n            <jats:p>Arteriogenesis is strongly dependent on the recruitment of leukocytes, especially monocytes, into the perivascular space of growing collateral vessels. On the basis of previous findings that platelets are central players in inflammatory processes and mediate the recruitment of leukocytes, the aim of this study was to assess the role of platelets in a model of arterial remodeling.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Approach and Results\u2014<\/jats:title>\n            <jats:p>\n              C57Bl6 wild-type mice,\n              <jats:italic>IL4-R\/Iba<\/jats:italic>\n              mice lacking the extracellular domain of the glycoprotein Ib\u03b1 (GPIb\u03b1) receptor, and mice treated with antibodies to block GPIb\u03b1 or deplete circulating platelets were studied in peripheral arteriogenesis. Using a novel model of intravital 2-photon and epifluorescence imaging, we visualized and quantified the interaction of platelets with leukocytes and the vascular endothelium in vivo. We found that transient platelet adhesion to the endothelium of collateral vessels was a major event during arteriogenesis and depended on GPIb\u03b1. Furthermore, leukocyte recruitment was obviously affected in animals with defective platelet GPIb\u03b1 function. In\n              <jats:italic>IL4-R\/Iba<\/jats:italic>\n              mice, transient and firm leukocyte adhesion to the endothelium of collateral vessels, as well as leukocyte accumulation in the perivascular space, were significantly reduced. Furthermore, we detected platelet\u2013leukocyte aggregates within the circulation, which were significantly reduced in\n              <jats:italic>IL4-R\/Iba<\/jats:italic>\n              animals. Finally, platelet depletion and loss of GPIb\u03b1 function resulted in poor reperfusion recovery as determined by laser Doppler imaging.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Thus, GPIb\u03b1-mediated interactions between platelets and endothelial cells, as well as leukocytes, support innate immune cell recruitment and promote arteriogenesis-establishing platelets as critical players in this process.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/atvbaha.114.304447","type":"journal-article","created":{"date-parts":[[2014,12,31]],"date-time":"2014-12-31T05:39:52Z","timestamp":1420004392000},"page":"589-597","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":38,"title":["Critical Role of Platelet Glycoprotein Ib\u03b1 in Arterial Remodeling"],"prefix":"10.1161","volume":"35","author":[{"given":"Sue","family":"Chandraratne","sequence":"first","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Luise","family":"von Bruehl","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith-Irina","family":"Pagel","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Stark","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eike","family":"Kleinert","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildiko","family":"Konrad","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Farschtschi","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Coletti","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"G\u00e4rtner","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omari","family":"Chillo","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle R.","family":"Legate","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lorenz","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Rutkowski","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Caballero-Martinez","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Starke","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Tirniceriu","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurenz","family":"Pauleikhoff","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Fischer","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Assmann","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josef","family":"Mueller-Hoecker","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry","family":"Ware","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Nieswandt","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Schaper","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Schulz","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Deindl","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Massberg","sequence":"additional","affiliation":[{"name":"From the Medizinische Klinik und Poliklinik I, Department of Cardiology (S.C., M.-L.v.B., K.S., I.K., S.F., R.C., F.G., K.R.L., M.L., A.T., C.S., S.M.), Walter-Brendel-Centre of Experimental Medicine (S.C., M.-L.v.B., J.-I.P., K.S., E.K., I.K., S.F., R.C., F.G., O.C., K.R.L., M.L., S.R., A.C.-M., A.T., L.P., C.S., E.D., S.M.), Department of Anaesthesiology (J.-I.P.), Department of Applied Physics (K.R.L.), and Institute of Pathology (G.A., J.M.-H.), Ludwig-Maximilians-Universit\u00e4t, Munich, Germany;..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.303929"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.80.6.829"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000202677.55012.a0"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.2002.2013"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1385\/CBB:43:1:001"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000141145.78900.44"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/abbs\/40.8.681"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0800fje"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2006.tb00290.x"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01098.2001"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-008-0760-x"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20012044"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-29423-5_5"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20112322"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1987.tb11367.x"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.87.12.1141"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00350.2007"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29499"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.12.1164"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3345"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2956"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1657598"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1357-2725(02)00280-7"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2004.05.008"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.190.6.803"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-03-0997"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.11.4106-4114.2000"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119877"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016094004084"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1089\/10430340460732517"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000126922.18222.F0"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.01.047"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00427580"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004280050039"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000170133.43608.37"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000252802.25497.b7"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(99)00241-5"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2005.08.001"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/35393"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200105058"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1616128"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(03)00098-7"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-009-0283-y"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm848"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0563fje"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118575"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.21.11877"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc3801.095588"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12144"},{"key":"e_1_3_5_51_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.10.3322"},{"key":"e_1_3_5_52_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-03-276311"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1614407"},{"key":"e_1_3_5_54_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.192.2.193"},{"key":"e_1_3_5_55_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-09-010629"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0605318"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.017012"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.220467"},{"key":"e_1_3_5_59_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0206087"},{"key":"e_1_3_5_60_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-08-304808"}],"container-title":["Arteriosclerosis, Thrombosis, and Vascular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/ATVBAHA.114.304447","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T23:02:28Z","timestamp":1715554948000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/ATVBAHA.114.304447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1161\/ATVBAHA.114.304447"],"URL":"https:\/\/doi.org\/10.1161\/atvbaha.114.304447","relation":{},"ISSN":["1079-5642","1524-4636"],"issn-type":[{"value":"1079-5642","type":"print"},{"value":"1524-4636","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"2014-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}