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One such micronutrient is the catechin class, which are naturally occurring compounds in plant foods, such as teas, cocoa, wine, pears, and apples. Recent evidence reveals that catechins may be a key mediator in cardiovascular health via mechanisms of blood pressure reduction, flow-mediated vasodilation, and atherosclerosis attenuation. This review evaluates the current literature on the interplay between catechins and cardiovascular disease, which may have important implications for nutrition counseling and pharmaceutical drug development.<\/jats:p>","DOI":"10.1161\/atvbaha.117.309048","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T01:17:40Z","timestamp":1490318260000},"page":"757-763","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":99,"title":["Catechins as Potential Mediators of Cardiovascular Health"],"prefix":"10.1161","volume":"37","author":[{"given":"Daniel R.","family":"Mangels","sequence":"first","affiliation":[{"name":"From the Hospital of the University of Pennsylvania, Department of Medicine, Philadelphia (D.R.M.); and Perelman School of Medicine at the University of Pennsylvania, Department of Medicine, Cardiovascular Division, Section of Vascular Medicine, Philadelphia (E.R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Emile R.","family":"Mohler","sequence":"additional","affiliation":[{"name":"From the Hospital of the University of Pennsylvania, Department of Medicine, Philadelphia (D.R.M.); and Perelman School of Medicine at the University of Pennsylvania, Department of Medicine, Cardiovascular Division, Section of Vascular Medicine, Philadelphia (E.R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.176158"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704173361601"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000437740.48606.d1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/1047-2797(94)00055-X"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101043440101"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2009.10"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.56"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3945\/jn.113.189407"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.12.1433"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/129.9.1662"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/74.2.227"},{"key":"e_1_3_3_13_2","first-page":"280","article-title":"Cocoa flavanols - measurement, bioavailability and bioactivity.","volume":"17","author":"Kwik-Uribe C","year":"2008","unstructured":"Kwik-Uribe C, Bektash RM. 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