{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T23:44:04Z","timestamp":1792885444434,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>The summit of the left ventricle (LV) is the most superior portion of the epicardial LV bounded by an arc from the left anterior descending coronary artery, superior to the first septal perforating branch to the left circumflex coronary artery. Ventricular arrhythmias (VAs) originating from this region may present challenges for catheter ablation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              We studied 27 consecutive patients with VAs originating from the LV summit. The great cardiac vein (GCV) divides this region between an inferior area accessible to ablation and a superior, inaccessible area. Successful ablation was achieved within the GCV in 14 patients and on the epicardial surface in 4. Ventricular prepotentials were recorded at the successful ablation site in 80% of these patients. In 5 patients, ablation was abandoned because of inaccessibility of the catheter to the myocardium or high impedance with radiofrequency application within the GCV. In the remaining 4 patients, epicardial mapping suggested VA origins in a region of low voltage that was located superior to the GCV (inaccessible area), and ablation was abandoned because of close proximity to the coronary arteries or high impedance. A right bundle-branch block, transition zone, R-wave amplitude ratio in leads III to II, Q-wave amplitude ratio in leads aVL to aVR, and S waves in lead V\n              <jats:sub>6<\/jats:sub>\n              accurately predicted the site of origin.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>LV summit VAs may be ablated within the GCV or inferior to the GCV on the epicardial surface, though sites superior to the GCV are usually inaccessible to ablation.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.110.939744","type":"journal-article","created":{"date-parts":[[2010,9,21]],"date-time":"2010-09-21T03:00:09Z","timestamp":1285038009000},"page":"616-623","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":297,"title":["Idiopathic Ventricular Arrhythmias Originating From the Left Ventricular Summit"],"prefix":"10.1161","volume":"3","author":[{"given":"Takumi","family":"Yamada","sequence":"first","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Thomas","family":"McElderry","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harish","family":"Doppalapudi","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Okada","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimasa","family":"Murakami","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuya","family":"Inden","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyoaki","family":"Murohara","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vance J.","family":"Plumb","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Neal","family":"Kay","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Disease (T.Y., H.T.M., H.D., V.J.P., G.N.K.), University of Alabama at Birmingham, Birmingham, Ala; the Division of Cardiology (T.O., Y.M.), Aichi Prefectural Cardiovascular and Respiratory Center, Ichinomiya, Japan; the Division of Cardiology (Y.Y.), Nagoya Dai-ni Red Cross Hospital, Cardiovascular Center, Nagoya, Japan; and the Department of Cardiology (N.Y., Y.I., T.M.), Nagoya University Graduate School of Medicine, Nagoya, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00004-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01767-3"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2005.40749.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.12.025"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.611640"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.006"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.09.029"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.01085.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.040"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/circep.107.742940"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/circep.108.795948"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2008.09.029"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01608.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-65983-6"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2005.50163.x"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-007-9160-7"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90375-1"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2000.tb07055.x"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.03211.x"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1993.tb04574.x"}],"container-title":["Circulation: Arrhythmia and Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.110.939744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T00:17:21Z","timestamp":1715559441000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCEP.110.939744"}},"subtitle":["Anatomic Concepts Relevant to Ablation"],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["10.1161\/CIRCEP.110.939744"],"URL":"https:\/\/doi.org\/10.1161\/circep.110.939744","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12]]},"assertion":[{"value":"2010-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-09-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-09-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}