{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:56:50Z","timestamp":1791129410724,"version":"4.1.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Pulmonary vein isolation (PVI) is an established treatment option for patients with drug refractory paroxysmal atrial fibrillation. A novel compliant endoscopic ablation system housing a 980-nm-diode laser allows for discrete point-by-point ablation enabling a true circumferential ablation line design. We sought to determine the feasibility and safety of a circumferential ablation using endoscopic ablation system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>\n                      Thirty patients (17 female; mean age, 58\u00b19 years) with a median paroxysmal atrial fibrillation history of 3 years (range, 1 to 17 years) were treated. PVI was achieved in 114 of 116 (98%) PVs (4 left common PVs), thereby achieving simultaneous PVI for separate ipsilateral PVs in 19 of 26 (73%) left PVs and 6 of 30 (20%) right PVs. The total procedure time was 250\u00b162 minutes. Procedure time decreased from 310\u00b159 to 220\u00b137 minutes (\n                      <jats:italic>P<\/jats:italic>\n                      =0.0001) between the first 10 and the last 20 cases. Mean fluoroscopy time was 30\u00b118 minutes. Twenty-seven patients underwent postoperative endoscopy showing no or minimal thermal lesions in the esophagus in 21 (78%) and 2 (7%), respectively. In 4 (15%) patients, an esophageal ulceration was found that healed without sequelae. One pericardial tamponade and 1 right-sided phrenic nerve palsy occurred. During a median follow-up of 168 days (113 to 203 days; q1-q3), 24 of 30 patients (80%) remained free of atrial fibrillation recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>Circumferential PVI using the novel compliant endoscopic ablation system was feasible in the majority of left PVs and minority of right PVs accompanied by a complication rate comparable to established approaches. To minimize the risk for thermal esophageal injury temperature monitoring is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circep.110.954149","type":"journal-article","created":{"date-parts":[[2010,7,25]],"date-time":"2010-07-25T20:12:36Z","timestamp":1280088756000},"page":"481-488","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":71,"title":["Feasibility of Circumferential Pulmonary Vein Isolation Using a Novel Endoscopic Ablation System"],"prefix":"10.1161","volume":"3","author":[{"given":"Boris","family":"Schmidt","sequence":"first","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Metzner","sequence":"additional","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Ryul Julian","family":"Chun","sequence":"additional","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dionysios","family":"Leftheriotis","sequence":"additional","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Yoshiga","sequence":"additional","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Fuernkranz","sequence":"additional","affiliation":[{"name":"From the Asklepios Klinik St Georg, Department of Cardiology, Hamburg, 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