{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:37:08Z","timestamp":1792730228794,"version":"4.5.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Steerable sheath technology is designed to facilitate catheter access, stability, and tissue contact in target sites of atrial fibrillation (AF) catheter ablation. We hypothesized that rhythm control after interventional AF treatment is more successful using a steerable as compared with a nonsteerable sheath access.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              One hundred thirty patients with paroxysmal or persistent drug-refractory AF undergoing their first ablation procedure were prospectively included in a randomized fashion in 2 centers. Ablation was performed by 10 operators with different levels of clinical experience. Treatment outcome was measured with serial 7-day Holter ECGs and additional symptom-based arrhythmia documentation. Single procedure success (freedom from AF and\/or atrial macroreentrant tachycardia) was significantly higher in patients ablated with a steerable sheath (78% versus 55% after 3 months,\n              <jats:italic>P<\/jats:italic>\n              =0.005; 76% versus 53% after 6 months,\n              <jats:italic>P<\/jats:italic>\n              =0.008). Rate of pulmonary vein isolation, procedure duration, and radiofrequency application time did not differ significantly, whereas fluoroscopy time was lower in the steerable sheath group (33\u00b114 minutes versus 45\u00b117 minutes,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). Complication rates showed no significant difference (3.2% versus 5%,\n              <jats:italic>P<\/jats:italic>\n              =0.608). On multivariable analysis, steerable sheath usage remained the only powerful predictor for rhythm outcome after 6 months of follow-up (hazard ratio, 2.837 [1.197 to 6.723]).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>AF catheter ablation using a manually controlled, steerable sheath for catheter navigation resulted in a significantly higher clinical success rate, with comparable complication rates and with a reduction in periprocedural fluoroscopy time.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Clinical Trial Registration\u2014<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">http:\/\/clinicaltrials.gov<\/jats:ext-link>\n              . Unique identifier: NCT00469638.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.110.957761","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T04:01:33Z","timestamp":1295496093000},"page":"157-165","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":105,"title":["Steerable Versus Nonsteerable Sheath Technology in Atrial Fibrillation Ablation"],"prefix":"10.1161","volume":"4","author":[{"given":"Christopher","family":"Piorkowski","sequence":"first","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Eitel","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha","family":"Rolf","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Bode","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Sommer","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gaspar","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Kircher","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Wetzel","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Shokor","family":"Parwani","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif-Hendrik","family":"Boldt","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meinhard","family":"Mende","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Bollmann","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Husser","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Dagres","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Esato","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Arya","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilhelm","family":"Haverkamp","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Hindricks","sequence":"additional","affiliation":[{"name":"From the Department of Electrophysiology (C.P., C.E., S.R., K.B., P.S., T.G., S.K., U.W., A.B., D.H., N.D., M.E., A.A., G.H.), Heart Center, University of Leipzig, Leipzig, Germany; the Department of Cardiology (A.S.P., L.-H.B., W.H.), Charit\u00e9, University Berlin Campus Virchow, Berlin, Germany; and the Coordination Center for Clinical Trials (M.M.), University of Leipzig, Leipzig, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn570"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.05.023"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.6.1611"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2008.12.009"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun147"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2009.01552.x"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.027"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.10.1312"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup331"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2008.01101.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.07.044"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2007.00760.x"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.10.003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.04.049"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.625"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.11.006"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.02.022"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.108.803650"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eup069"}],"container-title":["Circulation: Arrhythmia and Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.110.957761","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T23:58:20Z","timestamp":1715558300000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCEP.110.957761"}},"subtitle":["A Prospective, Randomized Study"],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1161\/CIRCEP.110.957761"],"URL":"https:\/\/doi.org\/10.1161\/circep.110.957761","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"2010-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-01-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}