{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:07:42Z","timestamp":1789614462550,"version":"build-2803163510"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Pediatric patients with persistent arrhythmias may require mechanical cardiopulmonary support. We sought to classify the population, spectrum, and success of current treatment strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>A multicenter retrospective chart review was undertaken at 11 sites. Inclusion criteria were (1) patients &lt;21 years, (2) initiation of mechanical support for a primary diagnosis of arrhythmias, and (3) actively treated on mechanical support. A total of 39 patients were identified with a median age of 5.5 months and median weight of 6 kg. A total of 69% of patients were cannulated for supraventricular tachycardia with a median rate of 230 beats per minute. A total of 90% of patients were supported with extracorporeal membrane oxygenation for an average of 5 days. The remaining 10% were supported with ventricular assist devices for an average of 38 (20\u201360) days. A total of 95% of patients were treated with antiarrhythmics, with 43% requiring &gt;1 antiarrhythmic. Amiodarone was the most frequently used medication alone or in combination. A total of 33% patients underwent electrophysiology study\/transcatheter ablation. Radiofrequency ablation was successful in 9 patients on full flow extracorporeal membrane oxygenation with 3 radiofrequency-failures\/conversion to cryoablation. One patient underwent primary cryoablation. A total of 15% of complications were related to electrophysiology study\/ablation. At follow-up, 23 patients were alive, 8 expired, and 8 transplanted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>Younger patients were more likely to require support in the presented population. Most patients were treated with antiarrhythmics and one third required electrophysiology study\/ablation. Radiofrequency ablation is feasible without altering extracorporeal membrane oxygenation flows. There was a low frequency of acute adverse events in patients undergoing electrophysiology study\/ablation, while on extracorporeal membrane oxygenation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circep.113.000973","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T05:56:38Z","timestamp":1404280598000},"page":"658-663","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Management of Pediatric Tachyarrhythmias on Mechanical Support"],"prefix":"10.1161","volume":"7","author":[{"given":"Jennifer N.A.","family":"Silva","sequence":"first","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher C.","family":"Erickson","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Carter","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Anne","family":"Greene","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Kantoch","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn K.","family":"Collins","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina Y.","family":"Miyake","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Carboni","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward K.","family":"Rhee","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Papez","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Anand","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy M.","family":"Bowman","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Van Hare","sequence":"additional","affiliation":[{"name":"From the Division of Pediatric Cardiology, Washington University School of Medicine, St Louis, MO (J.N.A.S., T.M.B., G.F.V.H.); Division of Pediatric Cardiology, Children\u2019s Hospital and Medical Center\/UNMC\/CUMC, Omaha, NE (C.C.E.); Division of Pediatric Cardiology, Children\u2019s Hospital of Minnesota, Minneapolis (C.D.C.); Division of Pediatric Cardiology, Children\u2019s National Medical Center, Washington, DC (E.A.G.); Division of Pediatric Cardiology, University of Alberta, Edmonton, Alberta, Canada (M.K..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3282f11f55"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000269030.57298.AF"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00130478-200301000-00010"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3182196cb1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1H148"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9734-5"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfq012"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12032"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.11.014"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.04.040"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.112.000685"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02343-4"}],"container-title":["Circulation: Arrhythmia and Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.113.000973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T20:01:22Z","timestamp":1715544082000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCEP.113.000973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1161\/CIRCEP.113.000973"],"URL":"https:\/\/doi.org\/10.1161\/circep.113.000973","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"2013-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}