{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T04:18:50Z","timestamp":1773980330174,"version":"3.50.1"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>To know the underlying mechanisms of J waves, the response to atrial pacing was studied in patients with idiopathic ventricular fibrillation (IVF) and patients with non-IVF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              In 8 patients with IVF, the J-wave amplitude was measured before, during, and after atrial pacing. All patients had episodes of ventricular fibrillation without structural heart disease. The responses of J waves were compared with those of the 17 non-IVF control subjects who revealed J waves but no history of cardiac arrest and underwent electrophysiological study. The IVF patients were younger than the non-IVF patients (28\u00b110 versus 52\u00b114 years, respectively;\n              <jats:italic>P<\/jats:italic>\n              =0.002) and had larger J waves with more extensive distribution. J waves decreased from 0.35\u00b10.26 to 0.22\u00b10.23 mV (\n              <jats:italic>P<\/jats:italic>\n              =0.025) when the RR intervals were shortened from 782\u00b188 to 573\u00b1162 ms (\n              <jats:italic>P<\/jats:italic>\n              =0.001). A decrease (\u22650.05 mV) in the J-wave amplitude was observed in 6 of the 8 patients. In addition, 1 patient showed a distinct reduction of J waves in the unipolar epicardial leads. In contrast, J waves were augmented in the 17 non-IVF subjects from 0.27\u00b10.09 to 0.38\u00b10.10 mV (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001): augmented in 9 and unchanged in the 8 subjects. The different response patterns of J waves to rapid pacing suggest different mechanisms: early repolarization in IVF patients and conduction delay in non-IVF patients.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>The response to atrial pacing was different between the IVF and non-IVF patients, which suggests the presence of different mechanisms for the genesis of J waves.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.117.005214","type":"journal-article","created":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T01:10:40Z","timestamp":1499476240000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":25,"title":["Tachycardia-Induced J-Wave Changes in Patients With and Without Idiopathic Ventricular Fibrillation"],"prefix":"10.1161","volume":"10","author":[{"given":"Yoshiyasu","family":"Aizawa","sequence":"first","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiji","family":"Takatsuki","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiko","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiro","family":"Kimura","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Kohsaka","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Kaneko","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuya","family":"Inden","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiko","family":"Takahashi","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nagase","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifusa","family":"Aizawa","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keichi","family":"Fukuda","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology, Keio University School of Medicine, Tokyo, Japan (Y.A., S.T., T.N., T.K., S.K., K.F.); Department of Cardiovascular Medicine Gunma University Graduate School of Medicine, Japan (Y.K.); Department of Cardiology, Nagoya University Graduate School of Medicine, Japan (Y.I.); Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan (N.T.); Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(61)90204-1"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.191096"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(76)90142-9"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00355-3"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(93)90550-S"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa071968"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.07.010"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90253-J"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.12.006"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.2.372"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.02.028"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02124.x"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2006.05.016"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0708182"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.11.010"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.09.012"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.014068"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.05.024"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.10.057"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.11.020"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc5001.100833"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-08-1111"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.10.044"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2004.04.006"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.07.187"}],"container-title":["Circulation: Arrhythmia and Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.117.005214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T23:22:36Z","timestamp":1715556156000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCEP.117.005214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1161\/CIRCEP.117.005214"],"URL":"https:\/\/doi.org\/10.1161\/circep.117.005214","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"2017-03-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e005214"}}