{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:12:07Z","timestamp":1783131127217,"version":"3.54.6"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Safety and feasibility data on transvenous lead extraction (TLE) in the challenging population of adults with congenital heart disease (A-CHD) are limited. Herein, we report the results of TLE in A-CHD during a 20-year period.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results:<\/jats:title>\n            <jats:p>\n              All consecutive TLE procedures in A-CHD were included in a monocentric prospective registry from 1996. A total of 121 leads were extracted in 49 A-CHD (median age, 38 years; 51% men) during 71 TLE procedures. Twenty-four (49%) patients had transposition of the great arteries. Main indications for extraction were infection in 34 (48%) and lead failure in 22 (31%). A laser sheath was required for 56 (46%) leads and a femoral approach for 10 (8%). Complete TLE was achieved for 111 leads (92%). In multivariable analysis, lead duration (odds ratio, 1.02; 95% confidence interval, 1.00\u20131.04;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) and number of previous cardiac surgeries (odds ratio, 2.65; 95% confidence interval, 1.52\u20134.67;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) were predictive of TLE failure. No perioperative death or pericardial effusion was observed. Subpulmonary atrioventricular valve regurgitation increased in 8 patients (5 with transposition of the great arteries) and was independently associated with an implantable cardioverter defibrillator lead (odds ratio, 9.69; 95% confidence interval, 1.31\u201371.64;\n              <jats:italic>P<\/jats:italic>\n              =0.03) and valvular vegetation (odds ratio, 7.29; 95% confidence interval, 1.32\u201340.51;\n              <jats:italic>P<\/jats:italic>\n              =0.02). After a median of 54 (19\u2013134) months of follow-up after the first TLE, 3 deaths occurred independently from lead management.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Despite complex anatomic issues, TLE can be achieved successfully in most A-CHD using advanced extraction techniques. Subpulmonary atrioventricular valve regurgitation is a prevalent complication, particularly in patients with transposition of the great arteries.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.117.005409","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T16:06:48Z","timestamp":1518451608000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Transvenous Lead Extraction in Adults With Congenital Heart Disease"],"prefix":"10.1161","volume":"11","author":[{"given":"Jean-Baptiste","family":"Gourraud","sequence":"first","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-A","family":"Chaix","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Shohoudi","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Pag\u00e9","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Dubuc","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Thibault","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy C.","family":"Poirier","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Dore","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Marcotte","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois-Pierre","family":"Mongeon","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita W.","family":"Asgar","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9da","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Khairy","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"Mond\u00e9sert","sequence":"additional","affiliation":[{"name":"From the Department of Medicine (J.-B.G., M.-A.C., P.P., M.D., B.T., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), Adult Congenital Heart Disease Center (M.-A.C., N.C.P., A.D., F.M., F.-P.M., A.W.A., R.I., P.K., B.M.), and Coordination Center (A.S.), Montreal Heart Institute, Universit\u00e9 de Montr\u00e9al, 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Experience"],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1161\/CIRCEP.117.005409"],"URL":"https:\/\/doi.org\/10.1161\/circep.117.005409","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"2017-05-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-12-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e005409"}}