{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:07:46Z","timestamp":1787238466866,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Sympathetic denervation exerts protective effects against ventricular arrhythmias (VAs) induced by acute myocardial infarction. The results of a previous study indicated that the distal part of the ligament of Marshall (LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ) might be a sympathetic conduit between the left stellate ganglion (LSG) and the ventricles. The present study was designed to compare the effects between LSG and LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ablation on ischemia-induced VAs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Twenty-nine dogs were randomly divided into sham ablation group (group 1, n=9), LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ablation group (group 2, n=10), and LSG ablation group (group 3, n=10). Ablation was performed before occlusion of the left anterior coronary artery. Changes in the heart rate variability, serum norepinephrine, ventricular effective refractory period, and blood pressure induced by LSG stimulation were observed, and the occurrence of VAs was recorded. Immunostaining examinations of LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      were performed in dogs without ablation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      In group 2, LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ablation evidently attenuated blood pressure elevation induced by LSG stimulation. Both LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ablation and LSG ablation similarly prolonged ventricular effective refractory period and reduced the concentration of serum norepinephrine, the sympathetic index of heart rate variability, and the incidence of VAs compared with sham ablation. Abundant sympathetic nerve fibers were observed in LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      LOM\n                      <jats:sub>LSPV<\/jats:sub>\n                      ablation prevented acute myocardial infarction\u2013induced VAs with the same efficiency as LSG ablation, potentially by blocking the sympathetic pathway from the LSG to the heart.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circep.117.005945","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T05:15:25Z","timestamp":1524719725000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Ablation of the Ligament of Marshall and Left Stellate Ganglion Similarly Reduces Ventricular Arrhythmias During Acute Myocardial Infarction"],"prefix":"10.1161","volume":"11","author":[{"given":"Shan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiliang","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoying","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Hubei Key Laboratory of Cardiology, Wuhan, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruisong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Renmin Hospital of Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., H.J.)."},{"name":"Cardiovascular Research Institute, Wuhan University, China (S.L., X.Y., D.L., Z.Q., X.W., W.H., R.M., H.H., J.X., B.H., Z.L., 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Arrhythmia and Electrophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.117.005945","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T20:06:15Z","timestamp":1715544375000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCEP.117.005945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1161\/CIRCEP.117.005945"],"URL":"https:\/\/doi.org\/10.1161\/circep.117.005945","relation":{},"ISSN":["1941-3149","1941-3084"],"issn-type":[{"value":"1941-3149","type":"print"},{"value":"1941-3084","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"2017-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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