{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T11:15:26Z","timestamp":1783077326873,"version":"3.54.6"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Ventricular tachycardia ablation is often limited by insufficient lesion creation. A novel radiofrequency catheter with an expandable lattice electrode has a larger surface area capable of delivering higher currents at a lower density to potentially increase lesion dimensions without overheating.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>This 8F bidirectional irrigated catheter (Sphere-9, Affera Inc) has a 9 mm spherical lattice tip (\u201clattice\u201d) with an effective surface area 10-fold larger than standard linear catheters. Nine surface thermocouples provide temperature feedback to a proprietary high-current generator operating in a temperature-controlled mode. Ex vivo phase: in 11 bovine hearts, unipolar ablation at 30, 60, and 120 seconds was compared between the lattice (Tmax60\u00b0C) and a standard linear irrigated-tip catheter (40 W) at contact force of 10 g. In 5 porcine hearts, bipolar ablation was compared between the catheters (Tmax60\u00b0C versus 40 W; 60 seconds). In vivo phase: in 9 swine, ventricular ablation at Tmax60\u00b0C versus 40 W was performed for 60 seconds. In addition, direct tissue temperature at 3- and 7-mm tissue depth was measured in a thigh muscle preparation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Ex vivo: lattice produced deeper lesions at 30, 60, and 120 seconds application duration (6.7\u00b11.3 versus 4.8\u00b11.2 mm; 8.3\u00b11.4 versus 5.4\u00b10.8 mm; 10.0\u00b11.6 versus 6.1\u00b11.6 mm, respectively,\n              <jats:italic>P<\/jats:italic>\n              \u22640.001 for all). Bipolar lesions were deeper (15.8\u00b14.1 versus 10.5\u00b11.4 mm,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and more likely to be transmural (80% versus 0%,\n              <jats:italic>P<\/jats:italic>\n              =0.002). In vivo: lattice produced deeper lesions (10.5\u00b11.4 versus 6.5\u00b10.8 mm,\n              <jats:italic>P<\/jats:italic>\n              \u22640.001). Tissue temperature at 7 mm was higher with the lattice (+15.1\u00b12.4\u00b0C;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). The steam-pop occurrence was lower with the lattice (total: 4% versus 18%,\n              <jats:italic>P<\/jats:italic>\n              =0.02; in vivo 0% versus 14.2%,\n              <jats:italic>P<\/jats:italic>\n              =0.13).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>This novel radiofrequency system produces larger ventricular lesions compared with standard irrigated catheters and at a lower risk of tissue overheating. This may improve the efficacy of ventricular tachycardia ablation procedures while reducing the number of applications and procedural duration.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.119.007661","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T10:03:16Z","timestamp":1573466596000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":29,"title":["Novel Irrigated Temperature-Controlled Lattice Ablation Catheter for Ventricular Ablation"],"prefix":"10.1161","volume":"12","author":[{"given":"Ayelet","family":"Shapira-Daniels","sequence":"first","affiliation":[{"name":"Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (A.S.-D., M.B., H.Y., J.S., E.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Barkagan","sequence":"additional","affiliation":[{"name":"Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (A.S.-D., M.B., H.Y., J.S., E.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hagai","family":"Yavin","sequence":"additional","affiliation":[{"name":"Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (A.S.-D., M.B., H.Y., J.S., E.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Sroubek","sequence":"additional","affiliation":[{"name":"Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (A.S.-D., M.B., H.Y., J.S., E.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek Y.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Helmsley Center for Electrophysiology, Department of Cardiology, Icahn School of Medicine at Mount Sinai, NY (V.Y.R.)."},{"name":"Department of Cardiology, Hamolka Hospital, Prague, Czech Republic (V.Y.R., P.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Neuzil","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hamolka Hospital, Prague, Czech Republic (V.Y.R., P.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elad","family":"Anter","sequence":"additional","affiliation":[{"name":"Harvard-Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (A.S.-D., M.B., H.Y., J.S., E.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.04.001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61755-4"},{"key":"e_1_3_3_4_2","first-page":"314","volume-title":"Catheter Ablation of Cardiac Arrythmias: Basic Concepts and Clinical applications","author":"Stevenson WG","year":"2008","unstructured":"Stevenson, WG. 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