{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:33:50Z","timestamp":1790030030973,"version":"4.0.1"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>Left bundle branch pacing (LBBP) has emerged as a safe and effective alternative to right ventricular pacing. Traditionally, LBBP is performed with lumenless lead (LLL); however, the use of stylet-driven lead (SDL) is on rise. We aimed to assess acute success and procedural outcomes of SDL versus LLL for LBBP.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>One hundred consecutive patients with bradyarrhythmia, indication of cardiac resynchronization therapy, or ablate and pace strategy were randomized in a 1:1 fashion to the SDL and LLL arms. Tendril STS lead with a CPS Locator 3D catheter and SelectSecure 3830 lead with a C315HIS catheter were used in the SDL and LLL arms, respectively. LBBP was confirmed by standard criteria with measurements done on Labsystem Pro.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              Patients in the LLL arm were significantly younger (71.9\u00b111 versus 76.4\u00b18.9 years;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.02); all other baseline characteristics were not significantly different. Acute success in LBBP was similar with SDL versus LLL (90% versus 92%;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.7). In patients with successful LBBP, screw attempts were not significantly different between the groups (2.3\u00b11.7 in SDL versus 1.9\u00b11.3 in LLL;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.2). Implant duration (11\u00b19.6 versus 9.9\u00b17.1 minutes;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.4), mean fluoroscopy dose (65.3\u00b182.7 versus 53.5\u00b150.5 mGy;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.5), and fluoroscopy time (7.8\u00b14.8 versus 7.4\u00b14 minutes;\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.7) were also not different in the SDL versus the LLL arm, respectively. Incidence of lead failure (\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.6), microdislodgement (\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =1), and macrodislodgement (\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.6) were not significantly different. Pacing threshold was comparable at implant and on follow-up at 1, 3, and 6 months.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>LBBP was feasible with both lead systems with similar success rate and low capture threshold. No significant difference was observed in procedure duration or fluoroscopy use. No major complications were recorded with either lead.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>REGISTRATION:<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.anzctr.org.au\">https:\/\/www.anzctr.org.au<\/jats:ext-link>\n              ; Unique identifier: ACTRN12624000304538.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circep.124.013385","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T10:00:29Z","timestamp":1732874429000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of Procedural Outcomes of Lumenless Fixed-Helix Versus Stylet-Driven Extendable-Helix Lead Systems in Left Bundle Branch Pacing: COMPARE LBBP"],"prefix":"10.1161","volume":"17","clinical-trial-number":[{"clinical-trial-number":"actrn12624000304538","registry":"10.18810\/anzctr"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8394-9710","authenticated-orcid":true,"given":"Jenish P.","family":"Shroff","sequence":"first","affiliation":[{"name":"The School of Medicine and Psychology, Australian National University, Australian Capital Territory (J.P.S., A.N., D.C.R., W.P.A., R.K.P.)."},{"name":"Canberra Heart Rhythm Centre, Australian Capital Territory (J.P.S., A.N., S.P.A., S.F., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3201-4824","authenticated-orcid":true,"given":"Anugrah","family":"Nair","sequence":"additional","affiliation":[{"name":"The School of Medicine and Psychology, Australian National University, Australian Capital Territory (J.P.S., A.N., D.C.R., W.P.A., R.K.P.)."},{"name":"Canberra Heart Rhythm Centre, Australian Capital Territory (J.P.S., A.N., S.P.A., S.F., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1104-5381","authenticated-orcid":true,"given":"Deep Chandh","family":"Raja","sequence":"additional","affiliation":[{"name":"The School of Medicine and Psychology, Australian National University, Australian Capital Territory (J.P.S., A.N., D.C.R., W.P.A., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreevilasam P.","family":"Abhilash","sequence":"additional","affiliation":[{"name":"Canberra Heart Rhythm Centre, Australian Capital Territory (J.P.S., A.N., S.P.A., S.F., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Fiorese","sequence":"additional","affiliation":[{"name":"Canberra Heart Rhythm Centre, Australian Capital Territory (J.P.S., A.N., S.P.A., S.F., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P.","family":"Ariyaratnam","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital, Australia (J.P.A., P.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4908-0641","authenticated-orcid":true,"given":"Walter P.","family":"Abhayaratna","sequence":"additional","affiliation":[{"name":"The School of Medicine and Psychology, Australian National University, Australian Capital Territory (J.P.S., A.N., D.C.R., W.P.A., R.K.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-8429","authenticated-orcid":true,"given":"Prashanthan","family":"Sanders","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital, Australia (J.P.A., P.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-100X","authenticated-orcid":true,"given":"Pugazhendhi","family":"Vijayaraman","sequence":"additional","affiliation":[{"name":"Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes-Barre, PA (P.V.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7391-6867","authenticated-orcid":true,"given":"Rajeev K.","family":"Pathak","sequence":"additional","affiliation":[{"name":"The School of Medicine and Psychology, Australian National University, Australian Capital Territory (J.P.S., A.N., D.C.R., W.P.A., R.K.P.)."},{"name":"Canberra Heart Rhythm Centre, Australian Capital Territory (J.P.S., A.N., S.P.A., S.F., 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