{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:25:39Z","timestamp":1787235939282,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Arrhythmia and Electrophysiology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Blocking a line depends not only on the ablation but also on the validation technique. We sought to compare the performance of different pacing modes for roof line validation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Fifty consecutive patients underwent atrial fibrillation ablation, which included a roof line and a floor line. Floor line block was mandatory for clear evaluation of the roof line, the block of which was demonstrated by a box isolation of the dome. Before floor line creation, first-pass roof line evaluation was based on high-density mapping while pacing from either: (1) the left appendage; (2) just above the line; or (3) with an overlapping multispline catheter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Roof line mapping was feasible in all patients (100%) during left appendage and nearby pacing, and in 45 (90%) patients during overlap pacing. Left appendage pacing sensitivity for true gaps was significantly lower than nearby (48% versus 97%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001) and overlap (48% versus 93%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001) pacing. Left appendage pacing negative predictive value for true block was significantly lower than nearby (50% versus 94%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.001) and overlap (50% versus 89%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.004) pacing. Double potentials during left appendage pacing were shorter than during nearby pacing (63\u00b120 ms versus 103\u00b122 ms;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001). In 1 patient, a slow conduction gap was unmasked only after floor line block. Final box isolation of the dome was achieved in 47 (94%) patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The longer the activation delay from one side of a line to the other, the greater the chance to unmask a slow conduction gap across the line. Nearby pacing thus better identifies roof line gaps than left appendage pacing. Overlap pacing offers a simple and fast alternative with similar performance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circep.124.013713","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T09:00:11Z","timestamp":1753434011000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Chasing Conduction Gaps Across the Roof Line: Nearby and Overlap Better Than Appendage Pacing"],"prefix":"10.1161","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6734-0569","authenticated-orcid":true,"given":"Takamitsu","family":"Takagi","sequence":"first","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2179-3786","authenticated-orcid":true,"given":"Osamu","family":"Inaba","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7027-2613","authenticated-orcid":true,"given":"Yukihiro","family":"Inamura","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5216-7107","authenticated-orcid":true,"given":"Akira","family":"Sato","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhei","family":"Isonaga","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3413-2629","authenticated-orcid":true,"given":"Shinichi","family":"Tachibana","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Ohya","sequence":"additional","affiliation":[{"name":"Japanese Red Cross Saitama Hospital, Japan (T.T., O.I., Y. Inamura, A.S., Y. Isonaga, S.T., H.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1782-9379","authenticated-orcid":true,"given":"Allan","family":"Plant","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. Ha\u00efssaguerre, T.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4093-0483","authenticated-orcid":true,"given":"Romain","family":"Tixier","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. Ha\u00efssaguerre, T.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4367-1117","authenticated-orcid":true,"given":"Josselin","family":"Duchateau","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. Ha\u00efssaguerre, T.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6189-1308","authenticated-orcid":true,"given":"Nicolas","family":"Derval","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. Ha\u00efssaguerre, T.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8348-9320","authenticated-orcid":true,"given":"Fr\u00e9d\u00e9ric","family":"Sacher","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. Ha\u00efssaguerre, T.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7957-8766","authenticated-orcid":true,"given":"M\u00e9l\u00e8ze","family":"Hocini","sequence":"additional","affiliation":[{"name":"H\u00f4pital Cardiologique Haut-L\u00e9v\u00eaque, CHU de Bordeaux. L\u2019Institut de RYthmologie et mod\u00e9lisation Cardiaque (LIRYC), Universit\u00e9 de Bordeaux, France (A.P., R.T., J.D., N.D., F.S., M. Hocini, P.J., M. 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