{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T02:55:49Z","timestamp":1790218549118,"version":"4.1.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Circ Genom Precis Med."],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1161\/circgen.118.002135","type":"journal-article","created":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T11:10:38Z","timestamp":1539601838000},"source":"Crossref","is-referenced-by-count":50,"title":["A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance"],"prefix":"10.1161","volume":"11","author":[{"given":"Inken G.","family":"Huttner","sequence":"first","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis W.","family":"Wang","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."},{"name":"Cardiology Department, St Vincent\u2019s Hospital, Darlinghurst, NSW, Australia (L.W.W., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine F.","family":"Santiago","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Horvat","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee","family":"Johnson","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delfine","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Medical Sciences, Bosch Institute, University of Sydney, Camperdown, NSW, Australia (D.C., F.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"von Frieling-Salewsky","sequence":"additional","affiliation":[{"name":"Institute of Physiology II, University of Muenster, Germany (M.v.F.-S., W.A.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Hillcoat","sequence":"additional","affiliation":[{"name":"Kevin Alford Cardiology, Port Macquarie, NSW Australia (K.H., K.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Bemand","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunjan","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip","family":"Braet","sequence":"additional","affiliation":[{"name":"School of Medical Sciences, Bosch Institute, University of Sydney, Camperdown, NSW, Australia (D.C., F.B.)."},{"name":"Cellular Imaging Facility, Charles Perkins Centre (F.B.)"},{"name":"Australian Centre for Microscopy and Microanalysis (F.B.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Hesselson","sequence":"additional","affiliation":[{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."},{"name":"University of Sydney, Camperdown, NSW, Australia. Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia (D.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Alford","sequence":"additional","affiliation":[{"name":"Kevin Alford Cardiology, Port Macquarie, NSW Australia (K.H., K.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Hayward","sequence":"additional","affiliation":[{"name":"Cardiac Physiology and Transplantation Division (C.S.H., M.P.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."},{"name":"Cardiology Department, St Vincent\u2019s Hospital, Darlinghurst, NSW, Australia (L.W.W., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.G.","family":"Seidman","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, MD (J.G.S.)."},{"name":"Department of Genetics, Harvard Medical School (J.G.S., C.E.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine E.","family":"Seidman","sequence":"additional","affiliation":[{"name":"Department of Genetics, Harvard Medical School (J.G.S., C.E.S.)."},{"name":"Cardiovascular Division, Brigham and Women\u2019s Hospital, Boston, MA (C.E.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Feneley","sequence":"additional","affiliation":[{"name":"Cardiac Physiology and Transplantation Division (C.S.H., M.P.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."},{"name":"Cardiology Department, St Vincent\u2019s Hospital, Darlinghurst, NSW, Australia (L.W.W., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang A.","family":"Linke","sequence":"additional","affiliation":[{"name":"Institute of Physiology II, University of Muenster, Germany (M.v.F.-S., W.A.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Fatkin","sequence":"additional","affiliation":[{"name":"Molecular Cardiology and Biophysics Division (I.G.H., L.W.W., C.F.S., C.H., R.J., T.J.B., G.T., D.F.)"},{"name":"Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. St Vincent\u2019s Clinical School, Faculty of Medicine, University of New South Wales, Kensington (I.G.H., L.W.W., C.F.S., D.H., C.S.H., M.P.F., D.F.)."},{"name":"Cardiology Department, St Vincent\u2019s Hospital, Darlinghurst, NSW, Australia (L.W.W., C.S.H., M.P.F., D.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng815"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110186"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010134"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.112.962928"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145284"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.09406"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3719"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu301"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa5458"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2009.04.014"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/163564"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000255758.69821.b5"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng816"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2013.12.020"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1242\/dev.139246"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.06.015"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.026989"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169007"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000029803.93022.93"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026053530766"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/res.86.1.59"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00255"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.01.025"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2017.12.012"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.114.301286"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1411493111"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1505517"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.0000143901.37063.2f"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000135591.37759.af"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.108.193326"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2014.10.020"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12551-017-0263-9"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.0208"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3843"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1030"}],"container-title":["Circulation: Genomic and Precision Medicine"],"original-title":[],"language":"en","deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T10:10:37Z","timestamp":1540375837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCGEN.118.002135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1161\/CIRCGEN.118.002135"],"URL":"https:\/\/doi.org\/10.1161\/circgen.118.002135","relation":{},"ISSN":["2574-8300","2574-8300"],"issn-type":[{"value":"2574-8300","type":"print"},{"value":"2574-8300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}