{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:08:34Z","timestamp":1781737714847,"version":"3.54.5"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Heart Failure"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>In 2007, the United Network for Organ Sharing changed the way centers were notified of possible organ donors. In the new system, a donor sequence number (DSN) was provided signifying the position of a recipient on the list for a particular donor. Whether high DSN donors have equivalent outcomes is unknown.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p>\n              The United Network for Organ Sharing database was queried between May 2007 and March 2014. DSNs were divided into cohorts of 5 (sequence 1\u20135, 6\u201310, and so forth). Survival was analyzed by Kaplan-Meier method. In this dataset, 12\u2009363 adult de novo heart transplants were performed, and the median DSN was 3 with 58.3% of donors allocated locally. The distance from donor to transplant hospital was \u2264500 miles in 93.8% of cases. With increasing DSN group, recipients were older, with longer ischemic time, and higher distance (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001 for all comparisons). As well, with increasing DSN, donors were increasingly older, female sex, mismatched gender (female donor with a male recipient), lower ejection fraction, hypertensive, and had a history of smoking, alcohol, or cocaine use. For the whole cohort, the 1-year and 5-year survivals were 89.7% and 74.8%, respectively. Survival based on various cut points of DSN was investigated; there was no difference regardless of DSN.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Most donors since 2007 were allocated within a close geographic range. DSN functions as a crowdsourced rank with most donors being selected within low numbers. Given the similar survival of donors at higher DSN, this represents an opportunity to increase transplant volumes.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circheartfailure.118.005823","type":"journal-article","created":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T09:00:17Z","timestamp":1558342817000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["What Number Are We?"],"prefix":"10.1161","volume":"12","author":[{"given":"David A.","family":"Baran","sequence":"first","affiliation":[{"name":"Advanced Heart Failure Center, Sentara Heart Hospital, Norfolk, VA (D.A.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Copeland","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson (H.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Copeland","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery, University of Arizona, Tucson (J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2015.10.023"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2016.08.017"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.000165"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13055"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2015.09.073"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.01.022"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2005.03.014"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2003.62"},{"key":"e_1_3_3_10_2","first-page":"735","article-title":"The alternate recipient list for heart transplantation: does it work?","volume":"16","author":"Laks H","year":"1997","unstructured":"Laks, H, Scholl, FG, Drinkwater, DC, Blitz, A, Hamilton, M, Moriguchi, J, Fonarow, G, Kobashigawa, J. The alternate recipient list for heart transplantation: does it work? J Heart Lung Transplant. 1997;16:735\u2013742.","journal-title":"J Heart Lung Transplant"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001573-200403000-00017"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.12.058"}],"container-title":["Circulation: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCHEARTFAILURE.118.005823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T01:10:58Z","timestamp":1715562658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCHEARTFAILURE.118.005823"}},"subtitle":["Donor Sequence and Outcomes of Heart Transplantation"],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1161\/CIRCHEARTFAILURE.118.005823"],"URL":"https:\/\/doi.org\/10.1161\/circheartfailure.118.005823","relation":{},"ISSN":["1941-3289","1941-3297"],"issn-type":[{"value":"1941-3289","type":"print"},{"value":"1941-3297","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"2018-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e005823"}}