{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:04:32Z","timestamp":1793289872955,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Heart Failure"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>Long-term outcomes and quality of life have been identified as core patient-centered outcomes for venoarterial extracorporeal membrane oxygenation (VA-ECMO) research. The aim of this study is to investigate the incidence of death or new disability at 12 months after the initiation of VA-ECMO.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>Prospective, multicenter, registry-embedded cohort study in 26 hospitals in Australia and New Zealand from February 2019 through April 2023. Adult patients admitted to a participating ICU and who underwent VA-ECMO were included. The primary outcome was death or new disability at 6 and 12 months. All results were adjusted for patient characteristics at the time of ECMO initiation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              Among 389 patients who received VA-ECMO (median age, 57 [44\u201365] years; 35% women), the incidence of death or new disability at 12 months was 70.6% compared with 70.8% at 6 months (adjusted odds ratio for 12 versus 6 months, 0.61 [95% CI, 0.25\u20131.49];\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.27). Compared with 6 months, at 12 months after VA-ECMO more patients were independent in activities of daily living (62.1% versus 48.2%; adjusted odds ratio, 2.84 [95% CI, 1.50\u20135.36];\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.001), and fewer patients were unemployed due to health reasons (32.7% versus 47.4%; adjusted odds ratio, 0.29 [95% CI, 0.13\u20130.65];\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              &lt;0.001). Differences in outcomes were found according to the reason for VA-ECMO initiation.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>At 12 months after VA-ECMO, 30% of patients are alive and without disability, with differences in outcome associated with the reason for VA-ECMO initiation. The major burden of disability appears to develop in the first 6 months after VA-ECMO initiation and is sustained between 6 and 12 months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>REGISTRATION:<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              ; Unique identifier: NCT03793257.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circheartfailure.124.012476","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T15:01:26Z","timestamp":1745938886000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Long-Term Functional Outcomes in the First 12 Months After VA-ECMO in Adult Patients: A Prospective, Multicenter Study"],"prefix":"10.1161","volume":"18","clinical-trial-number":[{"clinical-trial-number":"nct03793257","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1520-9387","authenticated-orcid":true,"given":"Ary","family":"Serpa Neto","sequence":"first","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, VIC, Australia (A.S.N., M.J.B., C.L.H.)."},{"name":"Department of Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil (A.S.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8295-7559","authenticated-orcid":true,"given":"Alisa M.","family":"Higgins","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5551-1401","authenticated-orcid":true,"given":"Michael J.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, VIC, Australia (A.S.N., M.J.B., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannah","family":"Anderson","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9793-2108","authenticated-orcid":true,"given":"Stephen","family":"Bernard","sequence":"additional","affiliation":[{"name":"Monash University, Melbourne, VIC, Australia (S.B., I.K.H., D.S.)."},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5289-032X","authenticated-orcid":true,"given":"Bentley J.","family":"Fulcher","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0553-5886","authenticated-orcid":true,"given":"Annalie","family":"Jones","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4727-547X","authenticated-orcid":true,"given":"Natalie J.","family":"Linke","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin V.","family":"Board","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0813-3145","authenticated-orcid":true,"given":"Daniel","family":"Brodie","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (D.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8452-2241","authenticated-orcid":true,"given":"Heidi","family":"Buhr","sequence":"additional","affiliation":[{"name":"Intensive Care Service, Royal Prince Alfred Hospital, Melbourne, VIC, Australia (H.B., D.J.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8430-9678","authenticated-orcid":true,"given":"Aidan J.C.","family":"Burrell","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5872-9051","authenticated-orcid":true,"given":"D. James","family":"Cooper","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1210-9914","authenticated-orcid":true,"given":"Eddy","family":"Fan","sequence":"additional","affiliation":[{"name":"Interdepartmental Division of Critical Care Medicine, University of Toronto, ON, Canada (E.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7012-2519","authenticated-orcid":true,"given":"John F.","family":"Fraser","sequence":"additional","affiliation":[{"name":"University of Queensland, Brisbane, QLD, Australia (J.F.F.)."},{"name":"Critical Care Research Group, Adult Intensive Care Society, Prince Charles Hospital, Brisbane, QLD, Australia (J.F.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Gattas","sequence":"additional","affiliation":[{"name":"Intensive Care Service, Royal Prince Alfred Hospital, Melbourne, VIC, Australia (H.B., D.J.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid K.","family":"Hopper","sequence":"additional","affiliation":[{"name":"Monash University, Melbourne, VIC, Australia (S.B., I.K.H., D.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8988-6482","authenticated-orcid":true,"given":"Sue","family":"Huckson","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Society, Melbourne, VIC, Australia (S.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5125-6829","authenticated-orcid":true,"given":"Edward","family":"Litton","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Fiona Stanley Hospital, Melbourne, VIC, Australia (E.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shay P.","family":"McGuinness","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Medical Research Institute of New Zealand, Wellington (S.P.M.G., R.L.P.)."},{"name":"Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, New Zealand (S.P.M.G., R.L.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7712-367X","authenticated-orcid":true,"given":"Priya","family":"Nair","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, St Vincent\u2019s Hospital, Sydney, NSW, Australia (P.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2285-9233","authenticated-orcid":true,"given":"Neil","family":"Orford","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Intensive Care Unit, University Hospital Geelong, Melbourne, VIC, Australia (N.O.)."},{"name":"School of Medicine, Deakin University, Melbourne, VIC, Australia (N.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4209-0334","authenticated-orcid":true,"given":"Rachael L.","family":"Parke","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Medical Research Institute of New Zealand, Wellington (S.P.M.G., R.L.P.)."},{"name":"Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, New Zealand (S.P.M.G., R.L.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3149-1936","authenticated-orcid":true,"given":"Vincent A.","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8939-7985","authenticated-orcid":true,"given":"David V.","family":"Pilcher","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Dicker","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3903-6293","authenticated-orcid":true,"given":"Benjamin A.J.","family":"Reddi","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Royal Adelaide Hospital, Melbourne, VIC, Australia (B.A.J.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8686-2709","authenticated-orcid":true,"given":"Dion","family":"Stub","sequence":"additional","affiliation":[{"name":"Monash University, Melbourne, VIC, Australia (S.B., I.K.H., D.S.)."},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7771-3760","authenticated-orcid":true,"given":"Tony V.","family":"Trapani","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6284-2022","authenticated-orcid":true,"given":"Andrew A.","family":"Udy","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9002-2075","authenticated-orcid":true,"given":"Carol L.","family":"Hodgson","sequence":"additional","affiliation":[{"name":"Australian and New Zealand Intensive Care Research Centre (A.S.N., A.M.H., M.J.B., S.A., B.J.F., N.J.L., A.J.C.B., D.J.C., S.P.M.G., N.O., R.L.P., D.V.P., C.D., T.V.T., A.A.U., C.L.H.), School of Public Health and Preventive Medicine"},{"name":"Department of Critical Care, Melbourne Medical School, University of Melbourne, Austin Hospital, VIC, Australia (A.S.N., M.J.B., C.L.H.)."},{"name":"Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (S.B., A.J., J.V.B., A.J.C.B., D.J.C., V.A.P., D.V.P., D.S., A.A.U., C.L.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the EXCEL Study Investigators on behalf of the International ECMO Network (ECMONet)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800385"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31047-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06290-1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4273-z"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066617737035"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003954"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005110"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc11811"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta14350"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2017707"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2011.04.024"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03821-0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(22)00248-X"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.51893\/2020.2.sur7"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.51893\/2021.1.OA10"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14444"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06438-7"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4830-0"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-023-01243-0"},{"key":"e_1_3_3_21_2","unstructured":"R Core Team. R: a language and environment for statistical computing Vienna Austria: R Foundation for Statistical Computing; 2021. Accessed January 4 2025. https:\/\/www.R-project.org\/."},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2015.10.020"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e318187bbd8"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-94637-z"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-022-01067-9"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.01.032"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2307227"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06248-3"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03794-0"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202110-2335OC"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-04041-w"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04770-6"},{"key":"e_1_3_3_33_2","unstructured":"World Health Organization. Accessed January 4 2025. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/rehabilitation."}],"container-title":["Circulation: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCHEARTFAILURE.124.012476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T18:00:45Z","timestamp":1750183245000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCHEARTFAILURE.124.012476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1161\/CIRCHEARTFAILURE.124.012476"],"URL":"https:\/\/doi.org\/10.1161\/circheartfailure.124.012476","relation":{},"ISSN":["1941-3289","1941-3297"],"issn-type":[{"value":"1941-3289","type":"print"},{"value":"1941-3297","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2024-09-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}