{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:25:08Z","timestamp":1789118708248,"version":"build-2803163510"},"reference-count":96,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Heart Failure"],"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Neurocognitive disorders\u2014including mild cognitive impairment, dementia, and delirium\u2014are common yet often underrecognized in heart failure, impairing self-care and outcomes. These heart failure\u2013related neurocognitive disorders pose a significant public health challenge due to high morbidity and mortality. Despite recent advances, timely detection, prevention, and intervention remain difficult. Most research focuses on pharmacological treatments, with limited attention to nonpharmacological approaches and mental health integration in heart failure care teams. Progress requires collaboration among internal medicine, surgery, nursing, and psychology. This review highlights interconnected pathways\u2014cerebral hypoperfusion, microvascular and endothelial dysfunction, thromboembolic injury, and neuroendocrine-inflammatory activation\u2014and discusses targeted interventions like simplified treatment plans, caregiver involvement, and multidisciplinary referrals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circheartfailure.126.014265","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:00:19Z","timestamp":1789117219000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Heart Failure and Neurocognitive Disorders: A Narrative Review"],"prefix":"10.1161","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2569-7016","authenticated-orcid":true,"given":"Shuantong","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China (S.L., Q.W., J.C.)."},{"name":"Medical School of Chinese People\u2019s Liberation Army, Beijing, China (S.L., Q.W., J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6458-0622","authenticated-orcid":true,"given":"Qian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China (S.L., Q.W., J.C.)."},{"name":"Medical School of Chinese People\u2019s Liberation Army, Beijing, China (S.L., Q.W., J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1218-4639","authenticated-orcid":true,"given":"Jiangbei","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China (S.L., Q.W., J.C.)."},{"name":"Medical School of Chinese People\u2019s Liberation Army, Beijing, China (S.L., Q.W., J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.15144"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2024.01.003"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2021.10.008"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-020-09463-3"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jrh.12919"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000000285"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11897-022-00564-z"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-016-9568-1"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-025-13257-z"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2023.38.e334"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.01.007"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-022-10290-2"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2017.04.007"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.2176"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-215368"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-025-04457-5"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2018.12.006"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2022.101354"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.01.022"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2025.02.007"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.122.010117"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.021978"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(02)00190-4"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjpad.2025.100224"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2025.e00535"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2021.12.014"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1100"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-018-0108-7"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2017.05.009"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu18020321"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/imt2.125"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-022-01452-3"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2024.10.006"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-326269"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020106320"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.06.046"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2025.06.055"},{"key":"e_1_3_3_39_2","first-page":"A10220597","article-title":"Incretin-based therapy of metabolic disease.","volume":"70","author":"Holst JJ","year":"2022","unstructured":"Holst JJ. Incretin-based therapy of metabolic disease. Dan Med J. 2022;70:A10220597.","journal-title":"Dan Med J"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-024-01090-x"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2025.e00712"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1177\/17562864241281903"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2025.06.058"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S348055"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02962-8"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-16-0367"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-015-9488-5"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.171"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000195751.94998.e3"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2005.02.003"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2008.10.020"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.04.028"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/chf.12025"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11897-017-0317-0"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-021-10118-5"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0000000000001083"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.124.068774"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2014.05.011"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2020.09.007"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.930121"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12287"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000213421"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.3390\/biom14020185"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2022.166511"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurjcn\/zvaf051"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.2174\/1381612821666150130124021"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2021.173851"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40256-020-00445-7"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000000216"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1111\/eci.70008"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-025-01233-1"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2378"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000000558"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2016.05.005"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4806.24.09070-0"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2025.111817"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs348"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2021.05.016"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-021-00935-z"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-019-0371-z"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv005"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-024-07534-4"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2014.12.004"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCN.0000000000001023"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2018.1510318"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.23736\/S1973-9087.21.07095-7"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.21-839"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-020-01928-7"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06490-3"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.7779"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.125.325686"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002149"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14061853"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2025.1581400"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanhl.2025.100762"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2023.1266955"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60461-5"}],"container-title":["Circulation: Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCHEARTFAILURE.126.014265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:00:20Z","timestamp":1789117220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCHEARTFAILURE.126.014265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,11]]},"references-count":96,"alternative-id":["10.1161\/CIRCHEARTFAILURE.126.014265"],"URL":"https:\/\/doi.org\/10.1161\/circheartfailure.126.014265","relation":{},"ISSN":["1941-3289","1941-3297"],"issn-type":[{"value":"1941-3289","type":"print"},{"value":"1941-3297","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,11]]},"assertion":[{"value":"2026-02-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e014265"}}