{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:30:23Z","timestamp":1791365423137,"version":"4.3.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Imaging"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Main pulmonary artery diameter (mPA) and ratio of mPA to ascending aorta diameter (ratio PA) derived from chest CT are commonly reported in clinical practice. We determined the age- and sex-specific distribution and normal reference values for mPA and ratio PA by CT in an asymptomatic community-based population.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              In 3171 men and women (mean age, 51\u00b110 years; 51% men) from the Framingham Heart Study, a noncontrast, ECG-gated, 8-slice cardiac multidetector CT was performed. We measured the mPA and transverse axial diameter of the ascending aorta at the level of the bifurcation of the right pulmonary artery and calculated the ratio PA. We defined the healthy referent cohort (n=706) as those without obesity, hypertension, current and past smokers, chronic obstructive pulmonary disease, history of pulmonary embolism, diabetics, cardiovascular disease, and heart valve surgery. The mean mPA diameter in the overall cohort was 25.1\u00b12.8 mm and mean ratio PA was 0.77\u00b10.09. The sex-specific 90th percentile cutoff value for mPA diameter was 28.9 mm in men and 26.9 mm in women and was associated with increase risk for self-reported dyspnea (adjusted odds ratio, 1.31;\n              <jats:italic>P<\/jats:italic>\n              =0.02). The 90th percentile cutoff value for ratio PA of the healthy referent group was 0.91, similar between sexes but decreased with increasing age (range, 0.82\u20130.94), though not associated with dyspnea.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>For simplicity, we established 29 mm in men and 27 mm in women as sex-specific normative reference values for mPA and 0.9 for ratio PA.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circimaging.111.968610","type":"journal-article","created":{"date-parts":[[2011,12,17]],"date-time":"2011-12-17T02:24:36Z","timestamp":1324088676000},"page":"147-154","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":300,"title":["Reference Values for Normal Pulmonary Artery Dimensions by Noncontrast Cardiac Computed Tomography"],"prefix":"10.1161","volume":"5","author":[{"given":"Quynh A.","family":"Truong","sequence":"first","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Massaro","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian S.","family":"Rogers","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir A.","family":"Mahabadi","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias F.","family":"Kriegel","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline S.","family":"Fox","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"O'Donnell","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udo","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"From the Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., I.S.R., A.A.M., M.F.K., U.H.); the Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (Q.A.T., C.J.O.); the Department of Mathematics, Boston University, Boston, MA (J.M.M.); the Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA (I.S.R.); West German Heart Center, Cardiology Department, University Clinic Essen,..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-198401000-00005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1076-6332(97)80111-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.71.850.10211060"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005382-199910000-00007"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-006-0122-9"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2009.02.013"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2342-11-7"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm021"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.5.2101039"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0058"},{"key":"e_1_3_3_12_2","first-page":"87","volume-title":"The Framingham Heart Study: An Epidemiologic Investigation of Cardiovascular Disease","author":"Cupples L","year":"1987","unstructured":"Cupples L, D'Agostino RS . Some risk factors related to the annual incidence of cardiovascular disease and death using pooled repeated biennial measurements: Framingham Study, 30-year follow-up. In: , Kannel WB, Wolf PA, Garrison RJ eds. The Framingham Heart Study: An Epidemiologic Investigation of Cardiovascular Disease. Washington, DC: NIH Publication; 1987: 87\u2013 203."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2273020369"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.110.956706"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.06.026"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.113.5.1250"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.crd.0000181619.87084.8b"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.5.1556"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2005.12.014"},{"key":"e_1_3_3_20_2","first-page":"1","article-title":"Pulmonary hypertension surveillance: United States, 1980\u20132002","volume":"54","author":"Hyduk A","year":"2005","unstructured":"Hyduk A, Croft JB, Ayala C, Zheng K, Zheng ZJ, Mensah GA . Pulmonary hypertension surveillance: United States, 1980\u20132002. MMWR Surveill Summ. 2005; 54: 1\u2013 28.","journal-title":"MMWR Surveill Summ."},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hco.0000142066.14966.85"}],"container-title":["Circulation: Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCIMAGING.111.968610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T01:17:31Z","timestamp":1715563051000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCIMAGING.111.968610"}},"subtitle":["The Framingham Heart Study"],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1161\/CIRCIMAGING.111.968610"],"URL":"https:\/\/doi.org\/10.1161\/circimaging.111.968610","relation":{},"ISSN":["1941-9651","1942-0080"],"issn-type":[{"value":"1941-9651","type":"print"},{"value":"1942-0080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"2011-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-12-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-12-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}