{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:40:21Z","timestamp":1791211221727,"version":"4.1.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Imaging"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Rheumatic heart disease (RHD) remains a major public health problem worldwide. Although early diagnosis by echocardiography may potentially play a key role in developing active surveillance, systematic evaluation of simple approaches in resource poor settings are needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>We prospectively compared focused cardiac ultrasound (FCU) to a reference approach for RHD screening in a school children population. FCU included (1) the use of a pocket-sized echocardiography machine, (2) nonexpert staff (2 nurses with specific training), and (3) a simplified set of echocardiographic criteria. The reference approach used standardized echocardiographic examination, reviewed by an expert cardiologist, according to 2012 World Heart Federation criteria. Among the 6 different echocardiographic criteria, first tested in a preliminary phase, mitral regurgitation jet length \u22652 cm or any aortic regurgitation was considered best suited to be FCU criteria. Of the 1217 subjects enrolled (mean, 9.6\u00b11 years; 49.6% male), 49 (4%) were diagnosed with RHD by the reference approach. The sensitivity of FCU for the detection of RHD was 83.7% (95% confidence interval, 73.3\u201394.0) for nurse A and 77.6% (95% confidence interval, 65.9\u201389.2) for nurse B. FCU yielded a specificity of 90.9% (95% confidence interval, 89.3\u201392.6) and 92.0% (95% confidence interval, 90.4\u201393.5) according to users. Percentage of agreement among nurses was 91.4%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>FCU by nonexperts using pocket devices seems feasible and yields acceptable sensitivity and specificity for RHD detection when compared with the state-of-the-art approach, thereby opening new perspectives for mass screening for RHD in low-resource settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circimaging.114.002324","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T23:02:55Z","timestamp":1420671775000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":84,"title":["Screening for Rheumatic Heart Disease"],"prefix":"10.1161","volume":"8","author":[{"given":"Mariana","family":"Mirabel","sequence":"first","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Bacquelin","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Tafflet","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Robillard","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Huon","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Corsenac","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"de Fr\u00e9micourt","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumar","family":"Narayanan","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Meunier","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baptiste","family":"No\u00ebl","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert Alain","family":"Hag\u00e8ge","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); D\u00e9partement de l\u2019Action..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Rouchon","sequence":"additional","affiliation":[{"name":"From the Paris Cardiovascular Research Center, INSERM U970, Paris, France (M.M., R.B., M.T., K.N., X.J., E.M.); Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology Department, European Georges Pompidou Hospital, Paris, France (M.M., A.A.H., X.J., E.M.); Cardiology and Development, Paris, France (M.M., X.J., E.M.); Agence Sanitaire et Sociale de Nouvelle Cal\u00e9donie, Noum\u00e9a, New Caledonia (C.R., B.H., P.C., J.-M.M., B.R.); 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