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The advent of 3-dimensional echocardiography, computed tomography, and cardiac magnetic resonance imaging overcoming these limitations provides new insights into mechanistic analysis of degenerative mitral regurgitation. This review will detail the contribution of quantitative and qualitative dynamic analysis of mitral annulus and mitral leaflets by new imaging methods in the understanding of degenerative mitral regurgitation pathophysiology.<\/jats:p>","DOI":"10.1161\/circimaging.116.005971","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T20:12:01Z","timestamp":1515615121000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":59,"title":["Pathophysiology of Degenerative Mitral Regurgitation"],"prefix":"10.1161","volume":"11","author":[{"given":"Clemence","family":"Antoine","sequence":"first","affiliation":[{"name":"From the Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN (C.A., F.M., G.B., S.V.M., J.F.M., H.I.M., M.E.-S.); and Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy 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