{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:27:34Z","timestamp":1790396854460,"version":"4.1.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Imaging"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Electromechanical discoordination may contribute to long-term pulmonary right ventricular (RV) dysfunction in patients after surgery for congenital heart disease. We sought to evaluate changes in RV function after temporary RV cardiac resynchronization therapy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Twenty-five patients aged median 12.0 years after repair of tetralogy of Fallot and similar lesions were studied echocardiographically (n=23) and by cardiac catheterization (n=5) after primary repair (n=4) or after surgical RV revalvulation for significant pulmonary regurgitation (n=21). Temporary RV cardiac resynchronization therapy was applied in the presence of complete right bundle branch block by atrial-synchronized RV free wall pacing in complete fusion with spontaneous ventricular depolarization using temporary electrodes. The q-RV interval at the RV free wall pacing site (mean 77.2% of baseline QRS duration) confirmed pacing from a late activated RV area. RV cardiac resynchronization therapy carried significant decrease in QRS duration (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) along with elimination of the right bundle branch block QRS morphology, increase in RV filling time (\n              <jats:italic>P<\/jats:italic>\n              =0.002), pulmonary artery velocity time integral (\n              <jats:italic>P<\/jats:italic>\n              =0.006), and RV maximum +dP\/dt (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), and decrease in RV index of myocardial performance (\n              <jats:italic>P<\/jats:italic>\n              =0.006). RV mechanical synchrony improved: septal-to-lateral RV mechanical delay decreased (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and signs of RV dyssynchrony pattern were significantly abolished. RV systolic stretch fraction reflecting the ratio of myocardial stretching and contraction during systole diminished (\n              <jats:italic>P<\/jats:italic>\n              =0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>In patients with congenital heart disease and right bundle branch block, RV cardiac resynchronization therapy carried multiple positive effects on RV mechanics, synchrony, and contraction efficiency.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circimaging.117.006424","type":"journal-article","created":{"date-parts":[[2017,9,7]],"date-time":"2017-09-07T04:30:27Z","timestamp":1504758627000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":57,"title":["Pulmonary Right Ventricular Resynchronization in Congenital Heart Disease"],"prefix":"10.1161","volume":"10","author":[{"given":"Jan","family":"Janou\u0161ek","sequence":"first","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Kovanda","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Lo\u017eek","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Tomek","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Vojtovi\u010d","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Gebauer","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kubu\u0161","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslav","family":"Krej\u010d\u00ed\u0159","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost","family":"Lumens","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammo","family":"Delhaas","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frits","family":"Prinzen","sequence":"additional","affiliation":[{"name":"From the Children\u2019s Heart Center, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic (J.J., J.K., M.L., V.T., P.V., R.G., P.K., M.K.); and CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, The Netherlands (J.L., T.D., F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.11.037"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.659664"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.09.090"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq249"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.08.009"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.06.029"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.113.001483"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01609-5"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000070930.33499.9F"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun178"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.11.019"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu281"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw414"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1880-4276(11)80019-0"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.05.010"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-2167(03)00008-8"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00106.2008"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00191.2013"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.01.025"},{"key":"e_1_3_3_21_2","first-page":"305","article-title":"Long-term precision of dual photon absorptiometry in the lumbar spine in clinical settings.","volume":"3","author":"Nilas L","year":"1988","unstructured":"Nilas L, Hassager C, Christiansen C. 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