{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T05:34:12Z","timestamp":1785821652101,"version":"3.56.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background\u2014<\/jats:italic>\n            <\/jats:bold>\n            In a number of coronary bifurcation lesions, both the main vessel and the side branch need stent coverage. Using sirolimus eluting stents, we compared 2 dedicated bifurcation stent techniques, the crush and the culotte techniques in a randomized trial with separate clinical and angiographic end-points.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods and Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            A total of 424 patients with a bifurcation lesion were randomized to crush (n=209) and culotte (n=215) stenting. The primary end point was major adverse cardiac events; cardiac death, myocardial infarction, target vessel revascularization, or stent thrombosis after 6 months. At 6 months there were no significant differences in major adverse cardiac event rates between the groups; crush 4.3%, culotte 3.7% (\n            <jats:italic>P<\/jats:italic>\n            =0.87). Procedure and fluoroscopy times and contrast volumes were similar in the 2 groups. The rates of procedure-related increase in biomarkers of myocardial injury were 15.5% in crush versus 8.8% in culotte group (\n            <jats:italic>P<\/jats:italic>\n            =0.08). A total of 324 patients had a quantitative coronary assessment at the index procedure and after 8 months. The angiographic end-points of in-segment and in-stent restenosis of main vessel and\/or side branch after 8 months were found in 12.1% versus 6.6% (\n            <jats:italic>P<\/jats:italic>\n            =0.10) and in 10.5% versus 4.5% (\n            <jats:italic>P<\/jats:italic>\n            =0.046) in the crush and culotte groups, respectively.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            Both the crush and the culotte bifurcation stenting techniques were associated with similar and excellent clinical and angiographic results. Angiographically, there was a trend toward less in-segment restenosis and significantly reduced in-stent restenosis following culotte stenting.\n          <\/jats:p>","DOI":"10.1161\/circinterventions.108.804658","type":"journal-article","created":{"date-parts":[[2009,2,11]],"date-time":"2009-02-11T04:30:44Z","timestamp":1234326644000},"page":"27-34","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":145,"title":["Randomized Comparison of Coronary Bifurcation Stenting With the Crush Versus the Culotte Technique Using Sirolimus Eluting Stents"],"prefix":"10.1161","volume":"2","author":[{"given":"Andrejs","family":"Erglis","sequence":"first","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indulis","family":"Kumsars","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Niemela\u0308","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Kervinen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Maeng","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens F.","family":"Lassen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pa\u030al","family":"Gunnes","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sindre","family":"Stavnes","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan S.","family":"Jensen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Gall\ufffde","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga","family":"Narbute","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dace","family":"Sondore","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Ma\u0308kikallio","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Ylitalo","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evald H.","family":"Christiansen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Ravkilde","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terje K.","family":"Steigen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Mannsverk","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; Division of Cardiology (M.N., M.S., T.M., K.Y.), Department of Internal Medicine, University of Oulu, Finland; Department of Cardiology (M.M., J.F.L., E.H.C., J.R., L.T.), Aarhus University Hospital, Skejby, Aarhus Denmark; Department of Cardiology (P.G., S.S.), The Feiring Clinic, Feiring, Norway; Department of Cardiology (J.S.J., A.G.), Gentofte University Hospital, Gentofte,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Thayssen","sequence":"additional","affiliation":[{"name":"From the Latvian Centre of Cardiology (A.E., I.K., I.N., D.S.), Paul Stradins Clinical University Hospital, Riga, Latvia; 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