{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:27:05Z","timestamp":1757701625796},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background\u2014<\/jats:italic>\n            <\/jats:bold>\n            Diabetes is a powerful predictor of adverse events in patients undergoing percutaneous coronary intervention. Drug-eluting stents reduce restenosis rates compared with bare metal stents; however, controversy remains regarding which drug-eluting stents provides greater benefit in patients with diabetes. Accordingly, we compared the safety and efficacy of sirolimus-eluting stents (SES) with paclitaxel-eluting stents (PES) among diabetic patients in a contemporary registry.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods and Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Using the National Heart, Lung, and Blood Institute Dynamic Registry, we evaluated 2-year outcomes of diabetic patients undergoing percutaneous coronary interventions with SES (\n            <jats:italic>n<\/jats:italic>\n            =677) and PES (\n            <jats:italic>n<\/jats:italic>\n            =328). Clinical and demographic characteristics, including age, body mass index, insulin use, left ventricular function, and aspirin\/clopidogrel use postprocedure, did not differ significantly between the groups except that PES-treated patients had a greater frequency of hypertension and hyperlipidemia. At the 2-year follow-up, no significant differences were observed between PES and SES with regard to safety or efficacy end points. PES- and SES-treated patients had similar rates of death (10.7% versus 8.2%,\n            <jats:italic>P<\/jats:italic>\n            =0.20), death and myocardial infarction (14.9% versus 13.6%,\n            <jats:italic>P<\/jats:italic>\n            =0.55), repeat revascularization (14.8% versus 17.8%,\n            <jats:italic>P<\/jats:italic>\n            =0.36), and stent thrombosis (1.3% versus 1.3%,\n            <jats:italic>P<\/jats:italic>\n            =0.95). After adjustment, no significant differences between the 2 stent types in any outcome were observed.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            PES and SES are equally efficacious and have similar safety profiles in diabetic patients undergoing percutaneous coronary interventions in clinical practice.\n          <\/jats:p>","DOI":"10.1161\/circinterventions.109.885996","type":"journal-article","created":{"date-parts":[[2010,1,27]],"date-time":"2010-01-27T05:09:50Z","timestamp":1264568990000},"page":"42-49","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Paclitaxel-Eluting Versus Sirolimus-Eluting Stents in Diabetes Mellitus"],"prefix":"10.1161","volume":"3","author":[{"given":"William M.","family":"Wolf","sequence":"first","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen A.","family":"Vlachos","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar C.","family":"Marroquin","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon S.","family":"Lee","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conrad","family":"Smith","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Anderson","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John T.","family":"Schindler","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"Holper","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Dawn","family":"Abbott","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David O.","family":"Williams","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren K.","family":"Laskey","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin E.","family":"Kip","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryl F.","family":"Kelsey","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh R.","family":"Mulukutla","sequence":"additional","affiliation":[{"name":"From the University of Pittsburgh Medical Center (W.M.W., H.A.V., O.C.M., J.S.L., C.S., W.D.A., J.T.S., S.F.K., S.R.M.), Pittsburgh, Pa; University of Texas\u2014Southwestern (E.M.H.), Dallas, Tex; Rhode Island Hospital (J.D.A.), Providence, RI; Brigham and Women\u2019s Hospital (D.O.W.), Boston, Mass; University of New Mexico (W.K.L.), Albuquerque, NM; University of South Florida (K.E.K.), Tampa, Fla."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.19.2570"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.91.4.979"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.7.765"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.04.004"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000116750.63158.94"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00467-7"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.051"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.562421"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.12.069"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2008.02.005"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044372"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.04.056"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-1377"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl412"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21700"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.028"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.01.104"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.01.074"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10764"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.0000223866.42883.3b"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.102.24.2945"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01430-8"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.685313"},{"key":"e_1_3_2_24_2","unstructured":"Dawkins KD. SYNTAX trial 12-month outcomes in subset of patients with diabetes. Presented at Transcatheter Cardiovascular Therapeutics 2008 Washington DC October 12\u201317 2008."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.09.010"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.17.2126"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60314-6"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00286-1"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.043"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.104.532242"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.02.039"}],"container-title":["Circulation: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.109.885996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:43:15Z","timestamp":1715568195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.109.885996"}},"subtitle":["A Report From the National Heart, Lung, and Blood Institute Dynamic Registry"],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1161\/CIRCINTERVENTIONS.109.885996"],"URL":"https:\/\/doi.org\/10.1161\/circinterventions.109.885996","relation":{},"ISSN":["1941-7640","1941-7632"],"issn-type":[{"value":"1941-7640","type":"print"},{"value":"1941-7632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"2010-01-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}