{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,22]],"date-time":"2026-02-22T01:34:01Z","timestamp":1771724041339,"version":"3.50.1"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Clinical outcomes after stent placement in patients with a history of metal allergy remain incompletely understood. We performed a single-center retrospective study to evaluate such outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Twenty-nine allergic patients who underwent coronary stent implantation were compared with a nonallergic group (n=250) matched for demographics and a propensity score for allergy to metal. Hypersensitivity to nickel was reported in 26 of 29 and chromium in 9 of 29. Patch testing performed in 11 of 29 patients was positive in all. Comparing allergy versus control subjects, there were no differences in number of segments treated (1.4\u00b10.7 versus 1.5\u00b10.7), stents placed (1.7\u00b11.1 versus 1.6\u00b10.9), and frequency of drug-eluting stent usage (52% versus 60%). In-hospital death (0% versus 0%), myocardial infarction (MI, 4% versus 3%,\n              <jats:italic>P<\/jats:italic>\n              =0.27), and 30-day death (3% versus 0%,\n              <jats:italic>P<\/jats:italic>\n              =0.53) and MI (3% versus 4%,\n              <jats:italic>P<\/jats:italic>\n              =0.71) were statistically similar. There were no differences in 4-year death (12% versus 13%), target lesion revascularization (TLR, 13 versus 17%,\n              <jats:italic>P<\/jats:italic>\n              =0.54), or death\/MI\/TLR (24% versus 34%,\n              <jats:italic>P<\/jats:italic>\n              =0.20). Clinically driven repeat angiography in 12 of 29 allergy patients revealed binary restenosis rates of 27% in bare metal stents and 0% in drug-eluting stents, with mean diameter in-stent restenosis of 36% and 8%, respectively. There was no change in circulating eosinophil and lymphocyte counts after stenting in the allergy group (0.19\u20130.20,\n              <jats:italic>P<\/jats:italic>\n              =0.67, and 1.90\u20131.79,\n              <jats:italic>P<\/jats:italic>\n              =0.59, respectively).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>A history of metal allergy was not associated with adverse early or late outcomes in this single-center study.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.111.966614","type":"journal-article","created":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T00:24:56Z","timestamp":1332980696000},"page":"220-226","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":42,"title":["Outcomes After Coronary Stent Implantation in Patients With Metal Allergy"],"prefix":"10.1161","volume":"5","author":[{"given":"Santiago","family":"Romero-Brufau","sequence":"first","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia J.M.","family":"Best","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"David R.","family":"Holmes","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verghese","family":"Mathew","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D.P.","family":"Davis","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurpreet S.","family":"Sandhu","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Lennon","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charanjit S.","family":"Rihal","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Gulati","sequence":"additional","affiliation":[{"name":"From the Division of Cardiovascular Diseases, Mayo Clinic, 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