{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:26Z","timestamp":1791410906396,"version":"4.3.3"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>To retrospectively investigate the potential cause of contained rupture of the aortic root in balloon-expandable transcatheter aortic valve implantation (TAVI) by means of pre- and postinterventional multislice computed tomography.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Seventy-two patients (mean age 82\u00b17 years, mean aortic valve area 0.69\u00b10.19 cm\n              <jats:sup>2<\/jats:sup>\n              ) underwent balloon-expandable TAVI using the EdwardsSAPIEN Transcatheter Heart Valve (23 mm, n=19; 26 mm, n=50; 29 mm, n=3). Aortic annulus dimensions were quantified by multislice computed tomography\u2013based cross-sectional area assessment and average diameter calculation (CAAD) before and after TAVI. Post-TAVI multislice computed tomography data sets were available in 65 patients; contained aortic root rupture was diagnosed in 3 patients. Pre-TAVI CAAD was 23.1\u00b11.8 mm; post-TAVI CAAD was 22.9\u00b11.3 mm. Median relative change in CAAD pre- and post-TAVI was \u22120.5% (interquartile range, 3.6%). Relative increase of 5% to 10% was observed in 4 patients (1 with contained rupture), relative increase &gt;10% in 2 patients, both with contained rupture. Mean relative oversizing, calculated as the relative difference in diameter between pre-TAVI CAAD and nominal diameter of the selected prosthesis, was 9.8%\u00b17.8%. Relative oversizing was significantly higher in patients with contained rupture compared with patients without contained rupture (24.6%\u00b15.4% versus 9.1%\u00b16.6%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). Relative oversizing \u226520% occurred in 6 patients (3 with contained rupture).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Contained rupture of the aortic root in balloon-expandable TAVI is associated with severe prosthesis oversizing. Multislice computed tomography\u2013based assessment of aortic annulus dimension in conjunction with adapted sizing guidelines may reduce the incidence of severe oversizing.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.111.967349","type":"journal-article","created":{"date-parts":[[2012,8,8]],"date-time":"2012-08-08T05:46:18Z","timestamp":1344404778000},"page":"540-548","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":150,"title":["Prosthesis Oversizing in Balloon-Expandable Transcatheter Aortic Valve Implantation Is Associated With Contained Rupture of the Aortic Root"],"prefix":"10.1161","volume":"5","author":[{"given":"Philipp","family":"Blanke","sequence":"first","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Rein\u00f6hl","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Schlensak","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Siepe","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Pache","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wulf","family":"Euringer","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Geibel-Zehender","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Bode","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Langer","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedhelm","family":"Beyersdorf","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); Department of Cardiology (J.R., A.G.-Z., C.B., M.Z.); and Department of Cardiovascular Surgery (C.S., M.S., F.B.), University Hospital Freiburg, Freiburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Zehender","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology (P.B., G.P., W.E., M.L.); 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