{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:27:20Z","timestamp":1761863240150},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>The regional variability of percutaneous coronary intervention (PCI) rates may be explained by variations in the medical treatment of stable coronary artery disease. We sought to determine whether greater regional use of antianginal medications in PCI patients is associated with lower regional rates of PCI.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Using CathPCI Registry and Dartmouth Atlas data, we examined patients undergoing elective PCI for stable coronary artery disease from January 1, 2009, through March 31, 2011, and calculated rates of providing \u22652 antianginal medicines before PCI. We regressed the hospital referral region rates of PCI per 1000 Medicare enrollees in 2007 on the regions\u2019 rates of providing \u22652 antianginal medications before PCI. Among 300\u2009772 PCI procedures, 32.8%, 48.3%, 16.1%, and 2.8% of patients were on 0, 1, 2, or \u22653 antianginal medications, respectively. The median rate of providing \u22652 antianginal medications before PCI was 18.9%. Although substantial variability existed across hospital referral regions in providing \u22652 antianginal medications and in rates of PCI from the Dartmouth Atlas, there was no association between the rates of PCI in each hospital referral region and the rates of \u22652 antianginal medications before PCI (Spearman \u03c1, 0.0277;\n              <jats:italic>P<\/jats:italic>\n              =0.64).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>We found no association between the intensity of antianginal therapy and the use of PCI across hospital referral regions, despite the variability of both. Opportunities likely exist in many regions to increase the use of antianginal therapy before proceeding to elective PCI, and more research is needed to explain observed variations in care.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.112.000215","type":"journal-article","created":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T04:58:20Z","timestamp":1375851500000},"page":"436-443","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Antianginal Therapy Before Percutaneous Coronary Intervention"],"prefix":"10.1161","volume":"6","author":[{"given":"William B.","family":"Borden","sequence":"first","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvin I.","family":"Mushlin","sequence":"additional","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Roe","sequence":"additional","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa A.","family":"McCoy","sequence":"additional","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita F.","family":"Redberg","sequence":"additional","affiliation":[{"name":"From the Department of Public Health, Weill Cornell Medical College, New York, NY (W.B.B., A.I.M.); Saint Luke\u2019s Mid America Heart Institute, University of Missouri, Kansas City, MO (J.A.S.); Duke Clinical Research Institute, Duke University, Durham, NC (M.T.R., L.A.M.); and Department of Medicine, University of California, San Francisco, CA (R.F.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070829"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.02.059"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.05.056"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.104.521864"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2011.1484"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072771"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.10.005"},{"key":"e_1_3_3_9_2","first-page":"53","article-title":"Appropriateness of percutaneous coronary intervention.","volume":"306","author":"Chan PS","year":"2011","unstructured":"Chan PS, Patel MR, Klein LW, Krone RJ, Dehmer GJ, Kennedy K, Nallamothu BK, Weaver WD, Masoudi FA, Rumsfeld JS, Brindis RG, Spertus JA. Appropriateness of percutaneous coronary intervention. JAMA. 2011;306:53\u201361.","journal-title":"JAMA"},{"key":"e_1_3_3_10_2","unstructured":"Dartmouth atlas of health care: coronary angiography per 1 000 medicare enrollees. http:\/\/www.dartmouthatlas.org\/tools\/downloads.aspx. 2007. Accessed December 3 2012."},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01372-9"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20910"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.07.083"},{"key":"e_1_3_3_14_2","first-page":"459","article-title":"The American College of Cardiology National Database: progress and challenges. American College of Cardiology Database Committee.","volume":"29","author":"Weintraub WS","year":"1997","unstructured":"Weintraub WS, McKay CR, Riner RN, Ellis SG, Frommer PL, Carmichael DB, Hammermeister KE, Effros MN, Bost JE, Bodycombe DP. The American College of Cardiology National Database: progress and challenges. American College of Cardiology Database Committee. J Am Coll Cardiol. 1997;29:459\u2013465.","journal-title":"J Am Coll Cardiol"},{"key":"e_1_3_3_15_2","unstructured":"American College of Cardiology National Cardiovascular Data Registry. www.ncdr.com. Accessed December 3 2012."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.07.020"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03530390027029"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.11.1329"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/circoutcomes.109.864736"},{"key":"e_1_3_3_20_2","unstructured":"The Dartmouth Atlas of Health Care. http:\/\/www.dartmouthatlas.org\/. Accessed December 3 2012."},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.601"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1205361"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.182.4117.1102"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0909253"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198211183072104"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.02761.x"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2009.0609"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.9.962"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/circoutcomes.110.958264"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000248132.15231.fe"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-5-201009070-00005"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000255248.79308.41"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.28.3.864"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.var.81"}],"container-title":["Circulation: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.112.000215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:19:00Z","timestamp":1715566740000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.112.000215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1161\/CIRCINTERVENTIONS.112.000215"],"URL":"https:\/\/doi.org\/10.1161\/circinterventions.112.000215","relation":{},"ISSN":["1941-7640","1941-7632"],"issn-type":[{"value":"1941-7640","type":"print"},{"value":"1941-7632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"2012-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}