{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:17:24Z","timestamp":1792761444411,"version":"4.5.0"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Stent fracture (SF) after drug-eluting stent implantation has recently become an important concern because of its potential association with in-stent restenosis and stent thrombosis. However, the incidence and clinical impact of SF after everolimus-eluting stent implantation remain unclear.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              A total of 1035 patients with 1339 lesions undergoing everolimus-eluting stent implantation and follow-up angiography 6 to 9 months after index procedure were analyzed. SF was defined as complete or partial separation of the stent, as assessed by plain fluoroscopy or intravascular ultrasound during follow-up. We assessed the rates of SF and major adverse cardiac events, defined as cardiac death, myocardial infarction, stent thrombosis, and clinically driven target lesion revascularization within 9 months. SF was observed in 39 of 1339 lesions (2.9%) and in 39 of 1035 patients (3.8%). Ostial stent location and lesions with hinge motion, tortuosity, or calcification were independent predictors of SF. The rate of myocardial infarction and target lesion revascularization were significantly higher in the SF group than in the non-SF group (5.1% versus 0.4%;\n              <jats:italic>P<\/jats:italic>\n              =0.018 and 25.6% versus 2.0%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001, respectively). Stent thrombosis was more frequently observed in the SF group than in the non-SF group (5.1% versus 0.4%;\n              <jats:italic>P<\/jats:italic>\n              =0.018). Major adverse cardiac events within 9 months were significantly higher in the SF group than in the non-SF group (25.6% versus 2.3%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>SF after everolimus-eluting stent implantation occurs in 2.9% of lesions and is associated with higher rate of major adverse cardiac events, driven by higher target lesion revascularization and stent thrombosis.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.112.969238","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T15:10:21Z","timestamp":1348672221000},"page":"663-671","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":88,"title":["Incidence and Clinical Impact of Stent Fracture After Everolimus-Eluting Stent Implantation"],"prefix":"10.1161","volume":"5","author":[{"given":"Shoichi","family":"Kuramitsu","sequence":"first","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Iwabuchi","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Haraguchi","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenori","family":"Domei","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumu","family":"Nagae","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Hyodo","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyohei","family":"Yamaji","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimitsu","family":"Soga","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Arita","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Shirai","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Kondo","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Ando","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koyu","family":"Sakai","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Goya","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Takabatake","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinjo","family":"Sonoda","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyoshi","family":"Yokoi","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumitoshi","family":"Toyota","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Nosaka","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakiyo","family":"Nobuyoshi","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (S.K., M.I., T.D., M.H., K.Y., Y.S., T.A., S.S., K.K., K.A., K.S., M.G., H.Y., H.N., M.N.); Division of Cardiology, Chidoribashi Hospital, Fukuoka, Japan (T.H., A.N., Y.T., F.T.); and the Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan School of Medicine, Kitakyushu, Japan (S.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012843"},{"key":"e_1_3_3_3_2","first-page":"315","article-title":"Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.","volume":"49","author":"Moses JW","year":"2003","unstructured":"Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O\u2019Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE; 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Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. 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