{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:20:11Z","timestamp":1770747611026,"version":"3.49.0"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Transcatheter valve-in-valve implantation is an established therapy for high-risk patients with failed surgical aortic bioprosthesis. There are limited data comparing outcomes of valve-in-valve implantation using different transcatheter heart valves (THV).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Patients included in the Valve-in-Valve International Data registry (VIVID) and treated with self-expanding THV devices were analyzed using centralized core laboratory blinded to clinical events. St. Jude Medical Portico versus Medtronic CoreValve were compared in a 1:2 fashion after propensity score matching. A total of 162 patients, Portico- (n=54) and CoreValve- (n=108) based valve-in-valve procedures comprised the study population with no significant difference in baseline characteristics (age, 79\u00b18.2 years; 60% women; mean STS [Society of Thoracic Surgery] score 8.1\u00b15.5%). Postimplantation, CoreValve was associated with a larger effective orifice area (1.67 versus 1.31 cm\n              <jats:sup>2<\/jats:sup>\n              ;\n              <jats:italic>P<\/jats:italic>\n              =0.001), lower mean gradient (14\u00b17.5 versus 17\u00b17.5 mm Hg;\n              <jats:italic>P<\/jats:italic>\n              =0.02), and lower core laboratory\u2013adjudicated moderate-to-severe aortic insufficiency (4.2% versus 13.7%;\n              <jats:italic>P<\/jats:italic>\n              =0.04), compared with Portico. Procedural complications including THV malpositioning, second THV requirement, or coronary obstruction were not significantly different between the 2 groups. Survival and stroke rates at 30 days were similar, but overall mortality at 1 year was higher among patients treated with Portico compared with CoreValve (22.6% versus 9.1%;\n              <jats:italic>P<\/jats:italic>\n              =0.03).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>In this first matched comparison of THVs for valve-in-valve implantations, Portico and CoreValve demonstrated differences in postprocedural hemodynamics and long-term clinical outcomes. Although this could be related to THV design characteristics, the impact of other procedural factors cannot be excluded and require further evaluation.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.116.004392","type":"journal-article","created":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T01:05:21Z","timestamp":1491959121000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Matched Comparison of Self-Expanding Transcatheter Heart Valves for the Treatment of Failed Aortic Surgical Bioprosthesis"],"prefix":"10.1161","volume":"10","author":[{"given":"Sami","family":"Alnasser","sequence":"first","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asim N.","family":"Cheema","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus","family":"Simonato","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Barbanti","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy","family":"Edwards","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Kornowski","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Horlick","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harindra C.","family":"Wijeysundera","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Testa","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Bedogni","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafid","family":"Amrane","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Pelletier","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Claude","family":"Laborde","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hildick-Smith","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Keun","family":"Kim","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Tchetche","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Agrifoglio","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan-Malte","family":"Sinning","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ad J.","family":"van Boven","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00eblle","family":"Kefer","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Frerker","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas M.","family":"van Mieghem","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Linke","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Worthley","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Asgar","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Sgroi","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Aziz","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim D.","family":"Danenberg","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. Aziz, A.C., J.G.W., D.D.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.S.); Rabin Medical Center, Tel Aviv, Israel (R.K.); Peter Munk Cardiac Center, Toronto, Canada (E.H.); Schulich Heart Centre, Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Canada (H.C.W.); Department of Cardiology, IRCCS Pol. S. Donato, Milan, Italy (L.T., F.B.); Medisch..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marino","family":"Labinaz","sequence":"additional","affiliation":[{"name":"From the St. Michael\u2019s Hospital, Toronto, Canada (S.A., A.N.C., J.E.); St. Paul\u2019s Hospital, Vancouver, Canada (M.S., M. 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