{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:49:12Z","timestamp":1791902952402,"version":"4.3.4"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Outcomes after right ventricle (RV) decompression in infants with pulmonary atresia with intact ventricular septum vary widely. Descriptions of outcomes are limited to small single-center studies.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Neonates undergoing RV decompression for pulmonary atresia with intact ventricular septum were included from 4 pediatric centers. Primary end point was reintervention post-RV decompression; secondary end points included circulation type at latest follow-up. Ninety-nine patients (71 with pulmonary atresia with intact ventricular septum and 28 with virtual atresia) underwent RV decompression at median 3 (25th\u201375th, 2\u20135) days of age. Seventy-one patients (72%) underwent at least 1 reintervention after decompression. Median duration of follow-up was 3 years (range, 1\u201310). Freedom from reintervention was 51% at 1 month and 23% at 3 years. In multivariable analysis, reintervention was associated with virtual atresia (hazard ratio [HR], 0.51; 95% confidence interval [CI], 0.28\u2013091;\n              <jats:italic>P<\/jats:italic>\n              =0.027), smaller RV length (HR, 0.94; 95% CI, 0.89\u20130.99;\n              <jats:italic>P<\/jats:italic>\n              =0.027), and \u2264mild tricuspid regurgitation (TR; HR, 3.58; 95% CI, 2.04\u20136.30;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). Patients undergoing surgical shunt or ductal stent were less likely to have virtual atresia (HR, 0.36; 95% CI, 0.15\u20130.85;\n              <jats:italic>P<\/jats:italic>\n              =0.02) and more likely to have higher RV end-diastolic pressure (HR, 1.07; 95% CI, 1.00\u20131.15;\n              <jats:italic>P<\/jats:italic>\n              =0.057) and \u2264mild TR (HR, 3.50; 95% CI, 1.75\u20137.0;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). Number of reinterventions was associated with \u2264mild TR (rate ratio, 1.87; 95% CI, 1.23\u20132.87;\n              <jats:italic>P<\/jats:italic>\n              =0.0037). Multivariable analysis indicated that &lt;2-ventricle circulation status was associated with \u2264mild TR (odds ratio, 18.6; 95% CI, 5.3\u201365.2;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and lower RV area (odds ratio, 0.81; 95% CI, 0.72\u20130.91;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Patients with pulmonary atresia with intact ventricular septum deemed suitable for RV decompression have a high reintervention burden although most achieve 2-ventricle circulation. TR \u2264mild at baseline is strongly associated with reintervention and &lt;2-ventricle circulation at medium-term follow-up. Degree of baseline TR may be an important marker of long-term outcomes in this population.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.116.004428","type":"journal-article","created":{"date-parts":[[2017,5,13]],"date-time":"2017-05-13T01:00:28Z","timestamp":1494637228000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":53,"title":["Outcomes After Decompression of the Right Ventricle in Infants With Pulmonary Atresia With Intact Ventricular Septum Are Associated With Degree of Tricuspid Regurgitation"],"prefix":"10.1161","volume":"10","author":[{"given":"Christopher J.","family":"Petit","sequence":"first","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C.","family":"Glatz","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athar M.","family":"Qureshi","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Sachdeva","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiraz A.","family":"Maskatia","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Justino","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Goldberg","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrita","family":"Mozumdar","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Whiteside","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay S.","family":"Rogers","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George T.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney","family":"McCracken","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Kelleman","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., B.H.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan H.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children\u2019s Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children\u2019s Hospital Medical Center, OH (W.W., L.S.R., 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Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.116.004428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:24:55Z","timestamp":1715567095000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.116.004428"}},"subtitle":["Results From the Congenital Catheterization Research 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