{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:11:01Z","timestamp":1715645461323},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Relative benefits of bioresorbable vascular scaffolds (BVS) compared with everolimus-eluting stents (EES) are expected to accrue after complete bioresorption.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>We built a decision analytic Markov model comparing BVS and EES for a contemporary percutaneous coronary intervention population. Procedure-related morbidity and outcome data from the available literature were used to derive model probabilities. The net benefit of BVS and EES was estimated in terms of quality-adjusted life expectancy. Under the assumption of no risk for device thrombosis and target lesion revascularization with BVS beyond 3 years, the equipoise in quality-adjusted life expectancy (12.86) between BVS and EES was achieved 19 years after implantation. The maximum tolerable excess risk of 3-year BVS thrombosis equalizing the model-predicted quality-adjusted life expectancy of BVS and EES at 10 years was 1.40, corresponding to an absolute tolerable rate of 1.45%.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>At the currently observed relative increase in device thrombosis and under the extreme hypothesis of no scaffold thrombosis and target lesion revascularization beyond 3 years, the incremental benefit of BVS over EES becomes apparent only after 19 years. This simulation suggests that there is a small degree of benefit that clinicians and decision-makers may expect from the first-generation BVS at the current risk of device thrombosis. Manufacturers should target scaffold thrombosis rates &lt;1.45% at 3 years to make their technologies attractive during a 10-year horizon.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.117.005768","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T01:10:52Z","timestamp":1515719452000},"update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Decision Analytic Markov Model Weighting Expected Benefits and Current Limitations of First-Generation Bioresorbable Vascular Scaffolds"],"prefix":"10.1161","volume":"11","author":[{"given":"Davide","family":"Capodanno","sequence":"first","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Buccheri","sequence":"additional","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Romano","sequence":"additional","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piera","family":"Capranzano","sequence":"additional","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Francaviglia","sequence":"additional","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Tamburino","sequence":"additional","affiliation":[{"name":"From the Cardiac-Thoracic-Vascular Department, Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele Presidio Ferrarotto, Catania, Italy (D.C., S.B., S.R., P.C., B.F., C.T.); and Department of General Surgery and Medical-Surgical Specialties, University of Catania, Italy (D.C., P.C., C.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.021539"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1509038"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1614954"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.031843"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31470-8"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M07_11"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx155"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.011"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028479"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV12I14A277"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2014.11.002"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.685313"},{"key":"e_1_3_2_14_2","first-page":"441","article-title":"Causes of death in patients undergoing percutaneous coronary intervention with drug-eluting stents in a real-world setting.","volume":"21","author":"Lee MS","year":"2009","unstructured":"Lee MS, Canan T, Perlowski A, Bhatia R, Jurewitz D, Tobis JM. Causes of death in patients undergoing percutaneous coronary intervention with drug-eluting stents in a real-world setting. J Invasive Cardiol. 2009;21:441\u2013445.","journal-title":"J Invasive Cardiol"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.03.071"},{"key":"e_1_3_2_16_2","first-page":"266","article-title":"Target lesion revascularization after bare-metal or drug-eluting stents: clinical presentations and outcomes.","volume":"22","author":"Hayes KR","year":"2010","unstructured":"Hayes KR, Applegate RJ, Sacrinty MT, Kutcher MA, Gandhi SK, Santos RM, Little WC. Target lesion revascularization after bare-metal or drug-eluting stents: clinical presentations and outcomes. J Invasive Cardiol. 2010;22:266\u2013270.","journal-title":"J Invasive Cardiol"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.03.013"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03091790"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.08.024"},{"key":"e_1_3_2_20_2","unstructured":"Hwang SJ Jang Y Yoon JIncidence predictors and outcome of stent thrombosis after successful drug-eluting stent implantation: results of a multi-center study from the Korea Stent Thrombosis Registry (KOS). Presented at Transcatheter Cardiovascular Therapeutics 2006."},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.903955"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.111.963546"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.2.195"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.03.020"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.12.021"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.055939"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.02.007"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.11.048"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv500"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc5001.100794"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001508"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn509"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X06290495"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.003610"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.04.010"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.12.279"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.12.017"}],"container-title":["Circulation: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.117.005768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:48:31Z","timestamp":1715568511000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.117.005768"}},"subtitle":["Implications for Manufacturers and Next Device Iterations"],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1161\/CIRCINTERVENTIONS.117.005768"],"URL":"https:\/\/doi.org\/10.1161\/circinterventions.117.005768","relation":{},"ISSN":["1941-7640","1941-7632"],"issn-type":[{"value":"1941-7640","type":"print"},{"value":"1941-7632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"2017-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}