{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T09:30:57Z","timestamp":1775640657609,"version":"3.50.1"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Because of shared risk factors between coronary artery disease and cerebrovascular disease, patients with a history of transient ischemic attack (TIA) or stroke are at greater risk of developing coronary artery disease, which may require percutaneous coronary intervention (PCI). However, there remains a paucity of research examining outcomes after PCI in these patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              We analyzed consecutive patients who underwent PCI between January 1, 2013, and March 31, 2016, at 47 Michigan hospitals and identified those with a history of TIA\/stroke. We used propensity score matching to adjust for differences in baseline characteristics and compared in-hospital outcomes between patients with and without a history of TIA\/stroke. We compared rates of 90-day readmission and long-term mortality in a subset of patients. Among 98\u2009730 patients who underwent PCI, 10\u2009915 had a history of TIA\/stroke. After matching (n=10\u2009618 per group), a history of TIA\/stroke was associated with an increased risk of in-hospital stroke (adjusted odds ratio, 2.04; 95% confidence interval, 1.41\u20132.96;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). There were no differences in the risks of other in-hospital outcomes. In a subset of patients with postdischarge data, a history of TIA\/stroke was associated with increased risks of 90-day readmission (adjusted odds ratio, 1.22; 95% confidence interval, 1.09\u20131.38;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and long-term mortality (hazard ratio, 1.23; 95% confidence interval, 1.07\u20131.43;\n              <jats:italic>P<\/jats:italic>\n              =0.005).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>A history of TIA\/stroke was common in patients who underwent PCI and was associated with increased risks of in-hospital stroke, 90-day readmission, and long-term mortality. Given the devastating consequences of post-PCI stroke, patients with a history of TIA\/stroke should be counseled on this increased risk before undergoing PCI.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.118.006400","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T09:05:27Z","timestamp":1528794327000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Outcomes After Percutaneous Coronary Intervention in Patients With a History of Cerebrovascular Disease"],"prefix":"10.1161","volume":"11","author":[{"given":"Chris","family":"Song","sequence":"first","affiliation":[{"name":"From the Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor (C.S.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devraj","family":"Sukul","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.S., M.S., H.S.G.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan","family":"Seth","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.S., M.S., H.S.G.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wohns","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Spectrum Health, Grand Rapids, MI (D.W.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon R.","family":"Dixon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Beaumont Hospital, Royal Oak, MI (S.R.D.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicklaus K.","family":"Slocum","sequence":"additional","affiliation":[{"name":"Grand Traverse Heart Associates, Department of Cardiology, Traverse Heart and Vascular, Traverse City, MI (N.K.S.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitinder S.","family":"Gurm","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor (D.S., M.S., H.S.G.)"},{"name":"Division of Cardiology, Department of Internal Medicine, VA Ann Arbor Healthcare System, MI (H.S.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.03.046"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2015.10.019"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706482"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200933"},{"key":"e_1_3_4_6_2","unstructured":"Vorapaxar [package insert]. 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